NCT05973045

Brief Summary

Minimally invasive applications are seen as the gold standard in today's gynecology practice and are frequently preferred by both patients and physicians. Less pain, shorter hospital stays, and better cosmetic results brought about by minimally invasive applications further increase their preference. One of these approaches is hysteroscopic interventions. Although hysteroscopy is a well-defined method, current research has focused on further reduction of pain. One of these methods is to warm the distention media at body temperature. theTaim of this study was to examine the effect of distention medium temperature on image quality, hyponatremia risk, and post-operative pain in operative hysteroscopy.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
244

participants targeted

Target at P75+ for not_applicable postoperative-pain

Timeline
5mo left

Started Sep 2023

Longer than P75 for not_applicable postoperative-pain

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress88%
Sep 2023Sep 2026

First Submitted

Initial submission to the registry

July 25, 2023

Completed
8 days until next milestone

First Posted

Study publicly available on registry

August 2, 2023

Completed
1 month until next milestone

Study Start

First participant enrolled

September 1, 2023

Completed
3.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 30, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 30, 2026

Last Updated

August 14, 2025

Status Verified

August 1, 2025

Enrollment Period

3.1 years

First QC Date

July 25, 2023

Last Update Submit

August 11, 2025

Conditions

Keywords

hysteroscopy

Outcome Measures

Primary Outcomes (1)

  • Post-operative pain

    Post operative pain will evalute with numeric pain rating scale The scale is scored from 0 to 10. 0 means no pain and 10 means the most severe pain experienced.

    3 hours

Secondary Outcomes (1)

  • Post operavite Na Value Change

    1 minute

Study Arms (2)

24 Centigrade Degree

ACTIVE COMPARATOR

Operative hysteroscopy will be performed at room temperature distention medium.

Procedure: Operative Hysteroscopy 24 Centigrade Degree

37 Centigrade Degree

ACTIVE COMPARATOR

Operative hysteroscopy will be performed using a heated distention medium.

Procedure: Operative Hysteroscopy 37 Centigrade Degree

Interventions

Operative hysteroscopy will be performed at room temperature distention medium.

24 Centigrade Degree

Operative hysteroscopy will be performed using a heated distention medium.

37 Centigrade Degree

Eligibility Criteria

Age18 Years - 65 Years
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • To be planned for operative hysteroscopy due to an endometrial polyp or type 0-1 myoma in the range of 2-3 cm
  • Having a vaginal delivery at least once before
  • Ability to communicate adequately in Turkish or English

You may not qualify if:

  • Pregnancy
  • Active vaginal, and cervical infection

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Sabahattin Anil Ari

Izmir, 35000, Turkey (Türkiye)

RECRUITING

MeSH Terms

Conditions

Pain, Postoperative

Condition Hierarchy (Ancestors)

Postoperative ComplicationsPathologic ProcessesPathological Conditions, Signs and SymptomsPainNeurologic ManifestationsSigns and Symptoms

Study Officials

  • Sabahattin A Ari, Asst. Prof.

    Izmir Bakircay University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Sabahattin A Ari, Asst. Prof.

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: Prospective Randomized Controlled Clinical Study
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Asst. Prof.

Study Record Dates

First Submitted

July 25, 2023

First Posted

August 2, 2023

Study Start

September 1, 2023

Primary Completion (Estimated)

September 30, 2026

Study Completion (Estimated)

September 30, 2026

Last Updated

August 14, 2025

Record last verified: 2025-08

Data Sharing

IPD Sharing
Will not share

IPD will not be published.

Locations