Nicotine and Tobacco Message Framing Among LGBT Young Adults

NCT05972941 | Completed Results DMC

• 3 other identifiers: OSU-230204R00CA260718-02NCI-2024-05891
• Study Type: interventional
• Target: 252
• Locations: 1 country
• Sites: 1

Brief Summary

This trial refines and evaluates how cultural targeting influences the effectiveness of anti-tobacco messages among lesbian, gay, bisexual, and transgender (LGBT) young adults at risk for the use of more than one tobacco product (polytobacco use). Polytobacco use is associated with nicotine dependence and tobacco use into adulthood, and is disproportionately high among LGBT young adults. This trial seeks to determine how cultural targeting can be applied to communicate polytobacco use risk to at-risk LGBT young adults.

Conditions

Tobacco-Related Carcinoma

Keywords

health communication; LGBT

Outcome Measures

Primary Outcomes (7)

• Visual Attention - Dwell Time

  Visual attention measured by dwell time (milliseconds) on areas of interest (AOI; e.g., text, graphic) within a stimuli was assessed via eye-tracking for each message (n=8). Dwell times on AOIs were summed for all stimuli viewed by each participant and averaged. Scores represent total average dwell time on AOIs across stimuli.

  During intervention on Day 1, on average 3 minutes

• Visual Attention - Time to First Fixation

  Time (milliseconds) to first fixation on areas of interest (text, graphic) within a stimuli was assessed via eye-tracking for each message (n=8). Time to first fixation on a specific AOI was summed for all stimuli viewed by each participant and averaged. Scores represent total average time to first fixation on AOIs across stimuli.

  During intervention on Day 1, on average 3 minutes.

• Perceived Message Effectiveness - Message Perceptions

  6-items on a 5-point scale where 1 = Not at all and 5 = Very much. Please rate each statement from 1 (not at all) to 5 (very much). These message are worth remembering. These messages grabbed my attention. These messages are powerful. These messages are convincing. These messages are meaningful. These messages are informative. Individual items are summed and averaged for a total score ranging from 1 to 5. Higher scores indicate a better outcome.

  Immediately post-exposure to intervention

• Perceived Message Effectiveness - Effects Perceptions

  6-items. 5-point scale where 1 = Strongly disagree to 5 = Strongly agree These messages discourage me from smoking cigarettes. These messages make me concerned about the negative effects of smoking cigarettes These messages make smoking cigarettes seem unpleasant to me. 3-items above are summed and averaged. Higher scores indicate better outcome. These messages discourage me from vaping nicotine. These messages make me concerned about the negative effects of vaping nicotine. These messages make vaping nicotine seem unpleasant to me. 3-items above are summed and averaged for a total score ranging from 1 to 5. Higher scores indicate a better outcome.

  Immediately post-exposure to intervention

• Change in Behavioral Intentions

  8 items total. 4-point scale 1 = Definitely not to 4 = Definitely will. The following items were asked at baseline and post-exposure. How likely is it that in the next 3 months, you will refrain from vaping nicotine.... * completely and permanently? * when you get lonely? * when you are with your friends who use them? * when someone hands you a vape? How likely is it that in the next 3 months, you will refrain from smoking cigarettes... * completely and permanently? * when you get lonely? * when you are with your friends who use them? * when someone hands you a cigarette? For each subscale, pre-test and post-test items were summed and averaged. Change scores were calculated for each subscale by subtracting pre-test scores from post-test scores. Change scores could range from 0 to 3. Higher change scores indicate a better outcome (i.e. greater change in intentions to refrain from smoking or vaping)

  Change from Baseline in behavioral intentions immediately post-exposure to intervention

• Behavioral Intentions: Quitting Smoking

  Number of participants who answer "Yes" to the following: Do you plan to quit smoking cigarettes in the next 30 days? (Yes/No)

  Difference between conditions in behavioral intentions to quit smoking at 1-week follow-up after intervention exposure

• Behavioral Intentions to Quit Vaping

  Number of participants who answer "Yes" to the following: "Do you plan to quit vaping nicotine in the next 30 days?" (Yes/No)

  Difference between conditions in behavioral intentions to quit vaping at 1-week follow-up after intervention exposure

Secondary Outcomes (6)

• Reactance

  Immediately post-exposure to intervention

• Ad Relevance

  Immediately post-exposure to intervention

• Liking

  Immediately post-exposure to intervention

• Attitudes

  Immediately post-exposure to intervention

• Response Efficacy

  Immediately post-exposure to intervention

Study Arms (2)

Culturally targeted messages

EXPERIMENTAL

Participants will view 8 nicotine and tobacco health messages with LGBT culturally targeted messages and imagery

Behavioral: Health communications

Non-targeted messages

OTHER

Participants will view 8 nicotine and tobacco health messages with universal messages and imagery

Behavioral: Health communications

Interventions

Health communications BEHAVIORAL

Participants will view eight culturally targeted or non-targeted health communications about the health risks of nicotine and tobacco use.

Culturally targeted messages; Non-targeted messages

Eligibility Criteria

• Age: 18 Years - 35 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Speaks English fluently
• Self-identifies as lesbian, gay, bisexual, transgender, queer, or another non- heterosexual orientation or non-binary gender identity
• Ever used e-cigarettes AND combustible cigarettes
• Currently uses e-cigarettes, combustible cigarettes, or both e-cigarettes and combustible cigarettes
• Resides in the United States
• Access to a laptop or desktop computer with a camera for virtual eye-tracking

You may not qualify if:

• Glaucoma
• Cataracts

Sponsors & Collaborators

• Ohio State University Comprehensive Cancer Center: lead
• National Institutes of Health (NIH): collaborator
• National Cancer Institute (NCI): collaborator

Study Sites (1)

The Ohio State University

Columbus, Ohio, 43210, United States

Location

Related Links

• The Jamesline

MeSH Terms

Interventions

Health Communication

Intervention Hierarchy (Ancestors)

Health Care Facilities Workforce and Services

Results Point of Contact

• Title: Dr. Joanne G. Patterson
• Organization: The Ohio State University College of Public Health

patterson.1191@osu.edu

614-247-1780

Study Officials

• Joanne G Patterson, PhD

  The Ohio State University College of Public Health

  PRINCIPAL INVESTIGATOR

Publication Agreements

• PI is Sponsor Employee: No
• Restrictive Agreement: No

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: June 26, 2023
• First Posted: August 2, 2023
• Study Start: June 19, 2023
• Primary Completion: January 29, 2024
• Study Completion: February 6, 2024
• Last Updated: June 18, 2025
• Results First Posted: June 18, 2025

Record last verified: 2025-06

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)