Effect of Fenugreek and Cumin Powder on Overweight and Obese People

NCT05966935 | Completed DMC

• 1 other identifier: Fenugreek and cumin powder
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

The objective of this study is to investigate the effect of fenugreek and cumin powder on the anthropometric indices of overweight and obese adults aged 18-30 years. This study design intends to answer following question: Will fenugreek and cumin powder mixture result in change of anthropometric measurements {Body Mass Index\[BMI\], Waist-Hip Ratio, Fat Mass

Conditions

Overweight and Obesity

Keywords

Fenugreek powder; Cumin powder; Body Composition; Anthropometric Indices

Outcome Measures

Primary Outcomes (4)

• weight change in kilograms

  Electronic weighing scale will be used to assess weight change in both groups

  change from baseline weight after 2 months

• Change in Body fat mass in kilograms and percentages

  body fat mass and percentage will be assessed through inbody analyzer 270

  change from baseline readings after 2 months

• Change in BMI in kg/m^2

  the BMI will be calculated using weight(kg) and height(m\^2)

  change from baseline reading after 2 months

• Change in Waist- Hip Ratio

  the WHR will be calculated using inbody analyzer 270

  change from baseline reading after 2 months

Secondary Outcomes (2)

• Change in Basal metabolic Rate( BMR)

  Change from baseline after 2 months

• change in Protein mass of body (grams)

  change from baseline reading after 2 months

Study Arms (2)

fenugreek cumin powder

EXPERIMENTAL

Overweight and Obese adults in this group will receive fenugreek cumin powder daily twice a day before morning and evening meals for 8 weeks

Combination Product: Fenugreek Cumin Powder

Control group

NO INTERVENTION

Overweight and obese participants in this group will not receive fenugreek and cumin powder or any intervention for 8 weeks

Interventions

Fenugreek Cumin Powder COMBINATION_PRODUCT

Fenugreek and Cumin seeds will be procured from the market. They will be cleaned of debris, winnowed, and grinded to fine powder passed through a mesh size of 30 for metal cleaning. 5g of fenugreek powder and 5g of cumin powder will be packed in packets. Participants in the intervention group will be instructed to consume the powder before breakfast and dinner with a glass of water.

fenugreek cumin powder

Eligibility Criteria

• Age: 18 Years - 30 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• overweight and obese( BMI\>23 kg/m\^2)

You may not qualify if:

• pregnant women
• Thyroid
• PCOS
• HTN
• fitness regime
• specific diet

Sponsors & Collaborators

• University of Veterinary and Animal Sciences, Lahore - Pakistan: lead

Study Sites (1)

University of Veterinary and Animal Sciences, Lahore

Lahore, 54000, Pakistan

Location

Related Publications (12)

• Khosla P, Gupta DD, Nagpal RK. Effect of Trigonella foenum graecum (Fenugreek) on blood glucose in normal and diabetic rats. Indian J Physiol Pharmacol. 1995 Apr;39(2):173-4.

  PMID: 7649611 BACKGROUND

• Geberemeskel GA, Debebe YG, Nguse NA. Antidiabetic Effect of Fenugreek Seed Powder Solution (Trigonella foenum-graecum L.) on Hyperlipidemia in Diabetic Patients. J Diabetes Res. 2019 Sep 5;2019:8507453. doi: 10.1155/2019/8507453. eCollection 2019.

  PMID: 31583253 BACKGROUND

• Hameed S, Arshad MS, Ahmad RS, Hussain G, Imran M, Arshad MU, Ahmed A, Imran M, Imran A. Potential preventive and protective perspectives of different spice powders and their mixtures in rat model. Lipids Health Dis. 2020 Apr 23;19(1):78. doi: 10.1186/s12944-020-01223-9.

  PMID: 32326942 BACKGROUND

• Khateeb S, Albalawi A, Alkhedaide A. Regulatory effect of diosgenin on lipogenic genes expression in high-fat diet-induced obesity in mice. Saudi J Biol Sci. 2021 Jan;28(1):1026-1032. doi: 10.1016/j.sjbs.2020.11.045. Epub 2020 Nov 18.

  PMID: 33424396 BACKGROUND

• Kumar P, Bhandari U, Jamadagni S. Fenugreek seed extract inhibit fat accumulation and ameliorates dyslipidemia in high fat diet-induced obese rats. Biomed Res Int. 2014;2014:606021. doi: 10.1155/2014/606021. Epub 2014 Apr 29.

  PMID: 24868532 BACKGROUND

• Laudadio V, Nasiri-Dehbaneh M, Bilal RM, Qotbi A, Javandel F, Ebrahimi A, Seidavi A, Slozhenkina M, Gorlov I, Dunne PG, Tufarelli V. Effects of different levels of dietary black cumin (Nigella sativa L.) and fenugreek (Trigonella foenum-graecum L.) and their combination on productive traits, selected blood constituents, microbiota and immunity of broilers. Anim Biotechnol. 2022 Oct;33(5):941-954. doi: 10.1080/10495398.2020.1853138. Epub 2020 Dec 16.

  PMID: 33325302 BACKGROUND

• Mathern JR, Raatz SK, Thomas W, Slavin JL. Effect of fenugreek fiber on satiety, blood glucose and insulin response and energy intake in obese subjects. Phytother Res. 2009 Nov;23(11):1543-8. doi: 10.1002/ptr.2795.

  PMID: 19353539 BACKGROUND

• Tavakoli-Rouzbehani OM, Faghfouri AH, Anbari M, Nikpayam O, PourMirzaei Olyaei H, Alizadeh M. Efficacy of Cuminum Cyminum supplementation on lipid profile and anthropometric parameters: A systematic review and meta-analysis of randomized controlled clinical trials. Phytother Res. 2022 Jan;36(1):380-394. doi: 10.1002/ptr.7327. Epub 2021 Nov 25.

  PMID: 34825421 BACKGROUND

• Peng Y, Sun Q, Xu W, He Y, Jin W, Yuan L, Gao R. Vitexin ameliorates high fat diet-induced obesity in male C57BL/6J mice via the AMPKalpha-mediated pathway. Food Funct. 2019 Apr 1;10(4):1940-1947. doi: 10.1039/c9fo00148d. Epub 2019 Mar 15.

  PMID: 30874277 BACKGROUND

• Said O, Saad B, Fulder S, Khalil K, Kassis E. Weight loss in animals and humans treated with "weighlevel", a combination of four medicinal plants used in traditional arabic and islamic medicine. Evid Based Complement Alternat Med. 2011;2011:874538. doi: 10.1093/ecam/nen067. Epub 2011 Jun 16.

  PMID: 18952688 BACKGROUND

• Sharma MS, Choudhary PR. Effect of Fenugreek Seeds Powder (Trigonella foenum-graecum L.) on Experimental Induced Hyperlipidemia in Rabbits. J Diet Suppl. 2017 Jan 2;14(1):1-8. doi: 10.3109/19390211.2016.1168905. Epub 2016 Apr 12.

  PMID: 27070043 BACKGROUND

• Yadav UC, Baquer NZ. Pharmacological effects of Trigonella foenum-graecum L. in health and disease. Pharm Biol. 2014 Feb;52(2):243-54. doi: 10.3109/13880209.2013.826247. Epub 2013 Oct 9.

  PMID: 24102093 BACKGROUND

MeSH Terms

Conditions

Overweight; Obesity

Condition Hierarchy (Ancestors)

Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Sanaullah Iqbal, PhD

  University of Veterinary and Animal Sciences Lahore, Punjab

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Model Details: Participants will be divided into two groups. One group will receive the Fenugreek Cumin Powder. The other group will not receive the powder

Study Record Dates

• First Submitted: July 14, 2023
• First Posted: August 1, 2023
• Study Start: September 15, 2023
• Primary Completion: November 20, 2023
• Study Completion: December 28, 2023
• Last Updated: July 9, 2024

Record last verified: 2024-07

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)