Nutrition and Movement to Improve Quality of Life With Knee Osteoarthritis

NCT05955300 | Active Not Recruiting

• 1 other identifier: NUMOQUA
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 2

Brief Summary

This project aims to evaluate the effects of an evidence-based training program in combination with an antiinflammatory dietetic intervention on quality of life for patients with knee osteoarthritis

Conditions

Osteo Arthritis Knee

Keywords

Knee; Osteoarthritis; Exercise therapy; Nutrition; Quality of life

Outcome Measures

Primary Outcomes (1)

• Knee Injury and Osteoarthritis Outcome Score (Quality of Life)

  Patient reported outcome measurement, Max: 100, Min: 0, Max is the best that can be achieved

  9 Month

Study Arms (2)

Training program and nutrition therapy

EXPERIMENTAL

The intervention group receive the GLA:D® training program for 6 weeks and a nutrition therapy for 9 months.

Other: Training program; Other: Nutrition therapy

Training program

ACTIVE COMPARATOR

The control group receive GLA:D® training program for 6 weeks and general information regarding a healthy life style for 9 months.

Other: Training program

Interventions

Training program OTHER

The GLAD training program consists of neuromuscular exercises for the core, the knee and the hip muscles and patient education. The New Nordic Diet is a plant-based nutrition thats aims to reduce systematic low-grad inflammation.

Training program; Training program and nutrition therapy

Nutrition therapy OTHER

Nutrition therapy based on the New Nordic Diet

Training program and nutrition therapy

Eligibility Criteria

• Age: 50 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Mild to moderate knee osteoarthritis

You may not qualify if:

• Musculosceletal disorders which obviates a participation in the training program
• kognitive deficits
• internal, neurological and mental diseases
• drug and/or alcohol abuse

Sponsors & Collaborators

• St. Pölten University of Applied Sciences: lead
• University of Vienna: collaborator
• Danube University Krems: collaborator

Study Sites (2)

Sankt Pölten University of Applied Sciences

Sankt Pölten, Lower Austria, 3100, Austria

Location

St. Poelten University of Applied Sciences

Sankt Pölten, 3100, Austria

Location

Related Publications (2)

• Chmelar S, Trubswasser U, Aubram T, Leitner G, Haas A, Neubauer O, Wagner KH, Wondrasch B, Hold E. Barriers and facilitators for consuming a plant-based diet in patients with knee osteoarthritis: a qualitative study. Front Nutr. 2026 Mar 13;13:1743219. doi: 10.3389/fnut.2026.1743219. eCollection 2026.

  PMID: 41909038 DERIVED

• Hold E, Chmelar S, Aubram T, Leitner G, Nehrer S, Neubauer O, Wagner KH, Wondrasch B. Nutrition and movement to improve quality of life in patients with knee osteoarthritis: the NUMOQUA study protocol for a randomised controlled trial. Trials. 2024 Apr 9;25(1):245. doi: 10.1186/s13063-024-08048-2.

  PMID: 38594710 DERIVED

MeSH Terms

Conditions

Osteoarthritis

Interventions

Nutrition Therapy

Condition Hierarchy (Ancestors)

Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases

Intervention Hierarchy (Ancestors)

Therapeutics

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: Clinical trial with 2 groups

Study Record Dates

• First Submitted: July 5, 2023
• First Posted: July 21, 2023
• Study Start: November 11, 2022
• Primary Completion: February 5, 2025
• Study Completion (Estimated): June 30, 2026
• Last Updated: April 30, 2026

Record last verified: 2025-05

Data Sharing

• IPD Sharing: Will not share

Locations

AU (2)