Effect of Mulligans Mobilization With Movement in Osteoarthritis Knee.

NCT05577403 | Completed DMC

• 1 other identifier: RRC-2021-17
• Study Type: interventional
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

To evaluate the effect of Mulligan's mobilization with movement in osteoarthritis of the knee.

Conditions

Osteo Arthritis Knee

Keywords

Isometric exercise; Osteoarthritis; Rehabilitation

Outcome Measures

Primary Outcomes (3)

• pain intensity

  Visual Analogue scale on 0 to10 cm

  6 weeks

• Range of Motion

  Standard goniometer.

  6 weeks

• Western Ontario and McMaster universities osteoarthritis (WOMAC) index

  Western Ontario and McMaster universities osteoarthritis scale

  6 weeks

Study Arms (2)

Experimental Group

EXPERIMENTAL

Mulligan's mobilization with movement added isometric strength training will be given 3 days a week for six weeks.

Behavioral: Mulligan's mobilization with movement MWM added isometric strength training

Control Group

ACTIVE COMPARATOR

Mobilization-added isometric strength training will be given 3 days a week for six weeks.

Behavioral: Mulligan's mobilization with movement MWM added isometric strength training

Interventions

Mulligan's mobilization with movement MWM added isometric strength training BEHAVIORAL

Mulligan's mobilization with movement added isometric exercise: the participants in the experimental group will receive a Mulligan's mobilization with movement added isometric exercise. Treatment will be given for the period of three weeks, for five days a week in both groups. Data will be collected before intervention and after 2nd \& 4th week of intervention.

Also known as: Sham MWM added isometric strength training

Control Group; Experimental Group

Eligibility Criteria

• Age: 40 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patient with knee OA with radiological evidence of grade 2 or 3 of the Kellgren and Lawrence scale.
• Age between 40-65 years, unilateral or bilateral involvement (in the case of bilateral involvement, the more symptomatic knee was included), and pain in and around the knee.

You may not qualify if:

• Patient will be excluded, if they had any deformity of the knee, hip, or back, had any central or peripheral nervous system involvement.
• They had received steroids or intra-articular injection within the previous three months, uncooperative patients.

Sponsors & Collaborators

• Majmaah University: lead
• King Saud University: collaborator

Study Sites (1)

Rehabilitation center, Majmaah University

Al Majma'ah, Riyadh Region, 15341, Saudi Arabia

Location

MeSH Terms

Conditions

Osteoarthritis

Condition Hierarchy (Ancestors)

Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases

Study Officials

• Shahnaz Hasan, PhD

  Majmah University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: BASIC SCIENCE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor

Model Details: Allocation: Randomized

Study Record Dates

• First Submitted: December 7, 2021
• First Posted: October 13, 2022
• Study Start: November 5, 2022
• Primary Completion: November 10, 2023
• Study Completion: November 14, 2023
• Last Updated: September 18, 2025

Record last verified: 2023-11

Data Sharing

• IPD Sharing: Will not share

Locations

SA (1)