NCT05943392

Brief Summary

Even though extensive research on the multisensory integration of auditory and visual stimuli has been carried out, the mechanisms of integration of tactile stimuli with other senses remain less known and understood. Furthermore, the brain mechanisms associated with active and dynamic tactile exploration of a surface have not been extensively studied. In the context of the development of human-computer interaction (HCI) technologies, understanding these mechanisms remains of vital importance for the realization of multisensory devices and to improve the user experience of the general population, but also to benefit the use by clinical populations, e.g., people with visual impairments. The planned experiment aims to study multisensory integration during the active and dynamic tactile exploration of a surface (a natural texture or the screen of a multisensory tactile device). The primary hypotheses are that simultaneous auditory and/or visual stimulation during active tactile exploration of a surface will help participants form a mental representation of the shape or texture they are exploring, and that the recorded brain activity will be compatible with multisensory integration mechanisms at the level of the cerebral cortex. The planned project will include (1) behavioral (psychophysical) experiments, to assess participants' performance in discriminating the spatio-temporal location of tactile, auditory, visual, audio-tactile, audio-visual, and audio-visual-tactile on the screen of a multisensory tactile device and (2) surface electroencephalography (EEG) recording experiments, which will be employed to study the cortical mechanisms of multisensory integration during active and dynamic tactile exploration .

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
200

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started May 2024

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 22, 2023

Completed
2 months until next milestone

First Posted

Study publicly available on registry

July 13, 2023

Completed
10 months until next milestone

Study Start

First participant enrolled

May 15, 2024

Completed
1.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2026

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2026

Completed
Last Updated

March 12, 2025

Status Verified

May 1, 2024

Enrollment Period

1.8 years

First QC Date

May 22, 2023

Last Update Submit

March 7, 2025

Conditions

Keywords

touchactive touchmultisensory integrationvisionauditionEEGpsychophysics

Outcome Measures

Primary Outcomes (4)

  • Threshold of the psychometric function (behavioural)

    Assessment of the threshold of the psychometric function fitted from participants' stimulus-response pairs (psychophysical detection/discrimination tasks) to tactile and/or auditory and/or visual stimulation.

    36 months

  • Slope of psychometric function (behavioural)

    Assessment of the slope of the psychometric function fitted from participants' stimulus-response pairs (psychophysical detection/discrimination tasks) to tactile and/or auditory and/or visual stimulation.

    36 months

  • EEG (event-related potentials)

    EEG responses to transient tactile and/or auditory and/or visual stimulation.

    36 months

  • EEG (frequency tagging)

    EEG responses to sustained/periodic tactile and/or auditory and/or visual stimulation.

    36 months

Study Arms (1)

Healthy volunteers

EEG recordings; behavioural data (psychophysics)

Other: EEG recordingOther: Psychophysics (behavioural experiments)

Interventions

EEG recording to assess cortical processing of non-painful tactile, auditory, and/or visual stimuli

Healthy volunteers

Behavioural experiments to assess perception of non-painful tactile, auditory, and/or visual stimuli

Healthy volunteers

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Healthy volunteers aged between 18 and 65 years

You may qualify if:

  • Aged between 18 and 65 years
  • Ability to provide informed consent
  • Self-reported normal audition, normal somatosensation, and normal or corrected-to-normal vision

You may not qualify if:

  • Evidence for a clinically-significant neurological disease on direct questioning
  • Medication acting on the peripheral or central nervous system.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

UCLouvain

Woluwe-Saint-Lambert, 1200, Belgium

RECRUITING

MeSH Terms

Interventions

Psychophysics

Intervention Hierarchy (Ancestors)

Diagnostic Techniques and ProceduresDiagnosisBehavioral SciencesBehavioral Disciplines and Activities

Central Study Contacts

André Mouraux, PhD

CONTACT

Giulia Liberati, PhD

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 22, 2023

First Posted

July 13, 2023

Study Start

May 15, 2024

Primary Completion

March 1, 2026

Study Completion

March 1, 2026

Last Updated

March 12, 2025

Record last verified: 2024-05

Data Sharing

IPD Sharing
Will not share

Locations