Use of Hand-held Dynamometry to Obtain Objective Measures of Lower Extremity Force Production With Chronic Stroke

NCT05941962 | Completed

• 1 other identifier: 230030
• Study Type: observational
• Target: 20
• Locations: 1 country
• Sites: 1

Brief Summary

This study wants to know if using handheld dynamometry (HHD) to test leg strength in persons who have had a stroke, will reduce mistakes and give therapists better information to use for therapy. This study will collect normal values of leg muscle peak force production, cumulative peak force production, and sustained peak force production in patients with chronic stroke.

Conditions

Chronic Stroke; Weakness, Muscle

Outcome Measures

Primary Outcomes (1)

• Hand-held Dynamometry Measurement of Average Force Production

  Average force production of lower extremity isometric strength measured in pounds (lb)

  1 year

Secondary Outcomes (1)

• Hand-held Dynamometry Measurement of Peak Force Production

  1 year

Other Outcomes (1)

• Hand-held Dynamometry Measurement of Time to Peak Force

  1 year

Study Arms (1)

Average Force Production

Average force production of bilateral lower extremities will be collected using the handheld dynamometer, Activbody Activ5.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Age 18 years or older \- Stroke \> 3 months

You may qualify if:

• Age 18 years or older
• Stroke \> 3 months
• Ability to follow two-step commands
• Ability to assume all test positions and maintain for duration of testing (i.e. upright seated, prone, side lying, supine)

You may not qualify if:

• Lower extremity contractures preventing full passive range of motion (ROM)
• Vital signs contraindicated for exercise (i.e. resting heart rate \> 100 bpm \< 50 bpm, resting systolic blood pressure \> 200 mmHg or \< 90 mmHg, resting diastolic blood pressure \> 110 mmHg, oxygen saturation \< 90%)
• Symptoms contraindicated for testing (i.e. shortness of breath, angina, dizziness, severe headache, sudden onset of numbness or weakness, painful calf suggestive of deep vein thrombosis)
• Active infection and/or injury at location of testing site
• Other diagnosed co-morbidities that would impact physical participation

Sponsors & Collaborators

• Vanderbilt University Medical Center: lead

Study Sites (1)

Vanderbilt University Medical Center

Nashville, Tennessee, 37209-2069, United States

Location

Related Publications (7)

• Andrews AW, Bohannon RW. Short-term recovery of limb muscle strength after acute stroke. Arch Phys Med Rehabil. 2003 Jan;84(1):125-30. doi: 10.1053/apmr.2003.50003.

  PMID: 12589633 RESULT

• Bakers JNE, van den Berg LH, Ajeks TG, Holleman MJ, Verhoeven J, Beelen A, Visser-Meily JMA, van Eijk RPA. Portable fixed dynamometry: towards remote muscle strength measurements in patients with motor neuron disease. J Neurol. 2021 May;268(5):1738-1746. doi: 10.1007/s00415-020-10366-9. Epub 2020 Dec 23.

  PMID: 33355879 RESULT

• Bohannon RW. Considerations and Practical Options for Measuring Muscle Strength: A Narrative Review. Biomed Res Int. 2019 Jan 17;2019:8194537. doi: 10.1155/2019/8194537. eCollection 2019.

  PMID: 30792998 RESULT

• Mentiplay BF, Perraton LG, Bower KJ, Adair B, Pua YH, Williams GP, McGaw R, Clark RA. Assessment of Lower Limb Muscle Strength and Power Using Hand-Held and Fixed Dynamometry: A Reliability and Validity Study. PLoS One. 2015 Oct 28;10(10):e0140822. doi: 10.1371/journal.pone.0140822. eCollection 2015.

  PMID: 26509265 RESULT

• Mentiplay BF, Tan D, Williams G, Adair B, Pua YH, Bower KJ, Clark RA. Assessment of isometric muscle strength and rate of torque development with hand-held dynamometry: Test-retest reliability and relationship with gait velocity after stroke. J Biomech. 2018 Jun 25;75:171-175. doi: 10.1016/j.jbiomech.2018.04.032. Epub 2018 Apr 27.

  PMID: 29731325 RESULT

• Merry K, Napier C, Chung V, Hannigan BC, MacPherson M, Menon C, Scott A. The Validity and Reliability of Two Commercially Available Load Sensors for Clinical Strength Assessment. Sensors (Basel). 2021 Dec 16;21(24):8399. doi: 10.3390/s21248399.

  PMID: 34960492 RESULT

• Shefner JM. Strength Testing in Motor Neuron Diseases. Neurotherapeutics. 2017 Jan;14(1):154-160. doi: 10.1007/s13311-016-0472-0.

  PMID: 27600518 RESULT

Related Links

• Short-term recovery of limb muscle strength after acute stroke. Archives of Physical Medicine and Rehabilitation
• Portable fixed dynamometry: Towards remote muscle strength measurements in patients with motor neuron disease.
• Assessment of lower limb muscle strength and power using hand-held and fixed dynamometry: A reliability and validity study.
• Assessment of isometric muscle strength and rate of torque development with hand-held dynamometry: Test-retest reliability and relationship with gait velocity after stroke.
• Strength testing in motor neuron diseases.

MeSH Terms

Conditions

Muscle Weakness

Condition Hierarchy (Ancestors)

Muscular Diseases; Musculoskeletal Diseases; Neuromuscular Manifestations; Neurologic Manifestations; Nervous System Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Primary Investigator

Study Record Dates

• First Submitted: June 5, 2023
• First Posted: July 12, 2023
• Study Start: June 5, 2023
• Primary Completion: July 26, 2025
• Study Completion: July 26, 2025
• Last Updated: February 11, 2026

Record last verified: 2025-05

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)