The Immediate Effect of Manual Therapy Application on Respiratory Functions in Healthy Young Individuals

NCT05934240 | Completed DMC

• 1 other identifier: HacettepeUEKC
• Study Type: interventional
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

Manual therapy techniques targeting the thoracic region are commonly used in clinical practice. It has been suggested that manual therapy interventions directed at the spine can increase mobility of the spine and chest wall, which may have a positive impact on lung functions. The potential positive effects of thoracic manipulation on respiratory system diseases such as chronic obstructive pulmonary disease (COPD) and asthma have been investigated and continue to be studied. Specifically, the results of studies investigating the physiological outcomes of this therapeutic approach in healthy adults are conflicting. The aim of this study is to investigate the short-term effects of thoracic manipulation and mobilization, as well as diaphragm mobilization, through a single session of manual therapy interventions on respiratory functions.

Conditions

Health Young Individuals

Keywords

Manual therapy; Respiratory function test; Physical activity

Outcome Measures

Primary Outcomes (3)

• Pulmonary Functions Test- FEV1 (Forced expiratory volume in the first second)

  The forced expiratory volume in 1 second (FEV1) is the volume of air (in liters) exhaled in the first second during forced exhalation after maximal inspiration.

  Change from before and 5 minutes after application

• Pulmonary Functions Test-FVC (Forced vital capacity)

  Forced vital capacity, the maximum amount of air you can forcibly exhale from your lungs after fully inhaling.

  Change from before and 5 minutes after application

• Pulmonary Functions Test- FEV1/FVC

  The FEV1/FVC ratio is the ratio of the forced expiratory volume in the first one second to the forced vital capacity of the lungs.

  Change from before and 5 minutes after application

Study Arms (2)

Experimental group

ACTIVE COMPARATOR

Diaphragmatic mobilization, toracic mobilization and manipulation

Other: Manual therapy group

Control group

PLACEBO COMPARATOR

Placebo mobilization and manipulation

Other: Sham-manual therapy

Interventions

Manual therapy group OTHER

Manual therapy will be applied to the diaphragm and thoracic region.

Experimental group

Sham-manual therapy OTHER

Sham-manual therapy will be applied to the diaphragm and thoracic region.

Control group

Eligibility Criteria

• Age: 18 Years - 25 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• be between the ages of 18-25,
• to be a studen

You may not qualify if:

• those who have any health problems
• those with orthopedic disorders
• those with systemic and cardiopulmonary diseases that would interfere with the evaluation

Sponsors & Collaborators

• Hacettepe University: lead

Study Sites (1)

Hacettepe University

Ankara, 06000, Turkey (Türkiye)

Location

Related Publications (1)

• Kucuk E, Tozcu D, Topaktas B, Coskun G. Immediate effects of manual therapy on respiratory functions in healthy young individuals: a randomized controlled trial. Sci Rep. 2024 Jul 29;14(1):17419. doi: 10.1038/s41598-024-68654-7.

  PMID: 39075156 DERIVED

MeSH Terms

Conditions

Motor Activity

Condition Hierarchy (Ancestors)

Behavior

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lecturer

Study Record Dates

• First Submitted: June 21, 2023
• First Posted: July 6, 2023
• Study Start: July 1, 2023
• Primary Completion: July 30, 2023
• Study Completion: August 15, 2023
• Last Updated: September 22, 2023

Record last verified: 2023-09

Locations

TU (1)