NCT05929378

Brief Summary

This study was designed to compare the outcome of 3 point with 1 point lightweight mesh fixation in TAPP surgery for patients with type Ⅲ gilbert inguinal hernia. The main outcome include seroma, chronic pain, recurrence, et al.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
351

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jan 2023

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2023

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

June 17, 2023

Completed
16 days until next milestone

First Posted

Study publicly available on registry

July 3, 2023

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 30, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 30, 2025

Completed
Last Updated

May 21, 2025

Status Verified

May 1, 2025

Enrollment Period

2.1 years

First QC Date

June 17, 2023

Last Update Submit

May 16, 2025

Conditions

Outcome Measures

Primary Outcomes (2)

  • recurrence

    Check for recurrence by clinical examination or ultrasound at 6 months postoperatively

    6 months

  • Postoperative pain

    The visual analog scale (VAS) was adopted for pain evaluation 2 days, 3 months, and 6 months postoperatively. The scale range from 0 to 10, with 0 meaning no pain and 10 meaning the worst pain.

    6 months

Secondary Outcomes (1)

  • postoperative complications

    6 months

Study Arms (2)

3-point fixation group

EXPERIMENTAL

Lightweight Mesh Fixation with 3-point Fixation. First fixation is in cooper ligament. Second fixation is in the back of rectus abdominis. Third fixation is in the later of tractus iliopubicus.

Procedure: Lightweight mesh fixation

1-point fixation group

ACTIVE COMPARATOR

Lightweight Mesh Fixation with 1-point Fixation in the back of rectus abdominis.

Procedure: Lightweight mesh fixation

Interventions

Lightweight mesh fixation in 3 points

1-point fixation group3-point fixation group

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Unilateral indirect inguinal hernia according to preoperative physical examination and imaging examination.

You may not qualify if:

  • Age below 18 years or older than 80. Direct hernia, femoral hernia, recurrent hernia, incarcerated hernia, strangulated hernia, and other types of hernias.
  • Patients not suitable for general anesthesia. Patients requiring open surgery; patients requiring emergency surgery Loss to follow-up or communication difficulties, or poor compliance.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Yunhong Tian

Nanchong, Sichuan, 637000, China

Location

MeSH Terms

Conditions

Hernia, InguinalChronic PainSeromaRecurrenceInfectionsHematoma

Condition Hierarchy (Ancestors)

Hernia, AbdominalHerniaPathological Conditions, AnatomicalPathological Conditions, Signs and SymptomsPainNeurologic ManifestationsSigns and SymptomsInflammationPathologic ProcessesDisease AttributesHemorrhage

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER GOV
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Director of Gastrointestinal, Colorectal and Hernia Surgery

Study Record Dates

First Submitted

June 17, 2023

First Posted

July 3, 2023

Study Start

January 1, 2023

Primary Completion

January 30, 2025

Study Completion

January 30, 2025

Last Updated

May 21, 2025

Record last verified: 2025-05

Locations