The Cranial-caudal Mixed Medial Approach for Laparoscopic Right Hemicolectomy

NCT05923151 | Completed

• 1 other identifier: SubeiH
• Study Type: interventional
• Target: 148
• Locations: 1 country
• Sites: 1

Brief Summary

To explore the feasibility and effectiveness of the cranial-caudal mixed medial approach in laparoscopic right hemicolectomy with complete mesocolic excision. Laparoscopic right hemicolectomy using the cranial-caudal mixed medial approach is safe and feasible, can shorten the operation time, reduce the risk of intraoperative bleeding, and has good clinical results.

Conditions

Intraoperative Blood Loss; Postoperative Complications; Pathology

Outcome Measures

Primary Outcomes (1)

• The operative time

  The length of operative time

  Surgery start (skin incision time) - Surgery end (suture incision end time)

Secondary Outcomes (1)

• Intraoperative blood loss

  Surgery start (skin incision time) - Surgery end (suture incision end time)

Other Outcomes (4)

• Number of lymph nodes cleaned

  3-5 days after surgery

• Anastomotic leakage

  Within 30 days after surgery

• Liver failure

  Within 30 days after surgery

Study Arms (2)

The cranial-caudal mixed medial approach group

EXPERIMENTAL

75 patients were diagnosed with right colon cancer and underwent the cranial-caudal mixed medial approach for laparoscopic right hemicolectomy with complete mesocolic excision.

Procedure: The cranial-caudal mixed medial approach

the medial approach group

OTHER

73 patients were diagnosed with right colon cancer and underwent the medial approach for laparoscopic right hemicolectomy with complete mesocolic excision.

Procedure: The cranial-caudal mixed medial approach

Interventions

The cranial-caudal mixed medial approach PROCEDURE

Expose the fusion fascia of Transverse colon mesocolon and stomach, and cut the gastrocolic ligament. The mesentery of Transverse colon was dissociated from the medial side to the lateral side along the gastroepiploic vessels to expose the branches of Henle's trunk and the right colon vessels. The dorsal mesentery of the small intestine is cut along the "yellow white line", and free cephalically along the Toldt space to separate the posterior space of the Ascending colon and the anterior space of the pancreas and duodenum behind the Transverse colon. The right colon blood vessels were dissected along SMV from the projection of ileocolic blood vessels, and the blood vessels were cut off by high ligation, and the lymph nodes at the root of Mesentery were cleared. Through a small incision in the middle of the abdomen, the right colon and mesentery were completely removed to complete digestive tract reconstruction.

The cranial-caudal mixed medial approach group; the medial approach group

Eligibility Criteria

• Age: 18 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age range: 18-70 years old
• Right colon cancer confirmed by colonoscopy and pathological diagnosis
• Single primary tumor without distal metastasis
• Laparoscopic operation

You may not qualify if:

• Age below 18 and above 70 years old
• Patients who need urgent surgery
• Persons with a history of malignant tumors
• Multiple primary tumors or distant metastases

Sponsors & Collaborators

• Jie Wang: lead
• Yangzhou University: collaborator

Study Sites (1)

Subei People's Hospital

Yangzhou, Jiangsu, 225000, China

Location

MeSH Terms

Conditions

Postoperative Complications

Condition Hierarchy (Ancestors)

Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: DOUBLE
• Who Masked: INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: June 9, 2023
• First Posted: June 28, 2023
• Study Start: February 1, 2017
• Primary Completion: June 30, 2022
• Study Completion: February 1, 2023
• Last Updated: June 28, 2023

Record last verified: 2023-06

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)