Cross-Education and Mirror Therapy for Upper Limb in Post-Stroke Patients

NCT05920031 | Unknown

• 1 other identifier: 012/0585850002023
• Study Type: interventional
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

This randomized controlled trial will investigate the potential synergistic effects of combining cross-education training with mirror therapy on strength and motor function in the more affected upper limb of post-stroke patients.

Conditions

Stroke

Outcome Measures

Primary Outcomes (2)

• Changes in Upper limb strength

  Upper limb strength (measured by hand-held dynamometry)

  Changes in Upper limb strength at baseline, 8 weeks, 16 weeks

• Changes in motor function

  motor function (measured by Fugl-Meyer Assessment)

  Changes in motor function at baseline, 8 weeks, 16 weeks

Secondary Outcomes (1)

• Changes in Quality of life

  Changes in Quality of life at baseline, 8 weeks, 16 weeks

Study Arms (4)

Cross-education training only

EXPERIMENTAL

Participants will perform resistance exercises at 60% of their 1 repetition maximum (1RM) with the less affected limb.

Other: Cross-education

Mirror therapy only

EXPERIMENTAL

Participants will perform bilateral upper limb movements while observing the reflection of the less affected limb in a mirror.

Other: Mirror therapy

Combined cross-education and mirror therapy

EXPERIMENTAL

Participants will perform resistance exercises with the less affected limb while observing its reflection in a mirror.

Other: Cross-education; Other: Mirror therapy

Conventional rehabilitation

ACTIVE COMPARATOR

Participants will receive conventional rehabilitation for post-stroke upper limb motor impairments.

Other: Conventional Physical Therapy

Interventions

Cross-education OTHER

Participants will perform resistance exercises at 60% of their 1 repetition maximum (1RM) with the less affected limb. The intervention will be performed three times per week for 8 weeks. Each session will consist of three sets of 15 repetitions of bicep curls, tricep extensions, and wrist flexion/extension exercises with a 1-minute rest period between sets. The exercises will be performed in a seated position, with the participant's forearm resting on a table and the therapist providing manual resistance. The therapist will be positioned in front of the participant.

Combined cross-education and mirror therapy; Cross-education training only

Mirror therapy OTHER

Participants will perform bilateral upper limb movements while observing the reflection of the less affected limb in a mirror. The intervention will be performed three times per week for 8 weeks. Each session will consist of 10 minutes of mirror therapy, with the participant seated in front of a mirror. The participant will perform various upper limb movements, such as reaching and grasping, while observing the mirror reflection of the less affected limb. The therapist will be positioned beside the participant, providing verbal cues and feedback as necessary.

Combined cross-education and mirror therapy; Mirror therapy only

Conventional Physical Therapy OTHER

articipants will receive conventional rehabilitation for post-stroke upper limb motor impairments, which may include exercises such as range of motion, stretching, and strengthening of the affected limb, as well as other therapies such as electrical stimulation or constraint-induced movement therapy. The intervention will be individualized for each participant and will be performed three times per week for 8 weeks. The frequency, duration, and intensity of the exercises will be gradually increased over the course of the intervention, based on the participant's progress. The exercises may be performed in a seated or standing position, depending on the participant's ability and preference. The therapist will be positioned in front of or beside the participant, providing verbal cues and feedback as necessary.

Conventional rehabilitation

Eligibility Criteria

• Age: 30 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Post-stroke patients with upper limb motor impairments
• Aged 30 years to 60 years old
• At least 3 months post-stroke
• Able to participate in the intervention

You may not qualify if:

• Severe cognitive impairments
• Visual impairments
• Any contraindications to the intervention

Sponsors & Collaborators

• Ahram Canadian University: lead

Study Sites (1)

Outpatient clinic of faculty of physical therapy, Ahram Canadian University

Al Ḩayy Ath Thāmin, Giza Governorate, 3221405, Egypt

RECRUITING

MeSH Terms

Conditions

Stroke

Interventions

Mirror Movement Therapy

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases

Intervention Hierarchy (Ancestors)

Physical Therapy Modalities; Rehabilitation; Therapeutics

Study Officials

• Amal Fawzy, Ph.d

  Faculty of Physical Therapy, Ahram Canadian University

  STUDY DIRECTOR

Central Study Contacts

Mohamed M ElMeligie, Ph.d

CONTACT

+201064442032; mohamed.elmeligie@acu.edu.eg

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lecturer of Physical Therapy and Director of Electromyography Lab

Study Record Dates

• First Submitted: June 16, 2023
• First Posted: June 27, 2023
• Study Start: June 28, 2023
• Primary Completion: October 20, 2024
• Study Completion: October 20, 2024
• Last Updated: June 27, 2023

Record last verified: 2023-06

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)