NCT05919771

Brief Summary

This research study is being conducted to understand the outcomes of participation in the Up ENDing Parkinson's rock climbing program (24 sessions, or twice per week for about 12 weeks) on walking \& mobility, hand strength \& dexterity, and psychological well-being in individuals with Parkinson's Disease (PD). The rock climbing sessions are administered and supervised by Up ENDing Parkinson's, and are tailored to the skill level of the participant. Participants will answer questionnaires and complete physical performance tests twice, first prior to beginning the sessions and then again after the 24 sessions have been completed.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
32

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Jul 2023

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 15, 2023

Completed
11 days until next milestone

First Posted

Study publicly available on registry

June 26, 2023

Completed
16 days until next milestone

Study Start

First participant enrolled

July 12, 2023

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 12, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 12, 2024

Completed
Last Updated

August 22, 2024

Status Verified

August 1, 2024

Enrollment Period

1.1 years

First QC Date

June 15, 2023

Last Update Submit

August 20, 2024

Conditions

Outcome Measures

Primary Outcomes (1)

  • Change in Community Mobility and Ambulation

    Test of specific tasks to be accomplished to walk forward on a level surface safely and efficiently as evidence by the Community Balance and Mobility Scale (CBMS). CBMS is scored from 0-96 with higher scores denoting better performance.

    Baseline and at 12 weeks

Secondary Outcomes (6)

  • Change in Agility

    Baseline and at 12 weeks

  • Change in Dexterity

    Baseline and at 12 weeks

  • Change in Reaction Time

    Baseline and at 12 weeks

  • Change in Apathy

    Baseline and at 12 weeks

  • Change in Resilience

    Baseline and at 12 weeks

  • +1 more secondary outcomes

Other Outcomes (2)

  • Change in Grip strength

    Baseline and at 12 weeks

  • Change in Quality of Life across Multiple Dimensions: Perception of difficulty with daily life across 8 dimensions of daily living

    Baseline and at 12 weeks

Interventions

Vertical ascent of a surface specifically designed to elicit the skills that might be required to scale a naturally occurring rock formation

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Adults over the age of 18 with mild-to moderate idiopathic Parkinson's disease

You may qualify if:

  • at least 18 years old
  • Diagnosis of Parkinson's disease
  • Hoehn \& Yahr score 1-3
  • able to speak and read in English;
  • able to ambulate at least 10 meters with no assistive device or human assistance

You may not qualify if:

  • neurological disease diagnosis other than PD;
  • uncontrolled cardiovascular, pulmonary, neurological, or metabolic disease which may impact the ability to exercise or in which exercise is contraindicated;
  • cognitive or psychiatric impairment precluding informed consent or ability to following instructions;
  • pregnancy;
  • inability to ambulate 10 meters without assistive device or human assistance

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Marymount University

Arlington, Virginia, 22201, United States

Location

Related Publications (1)

  • Osborne JA, Botkin R, Colon-Semenza C, DeAngelis TR, Gallardo OG, Kosakowski H, Martello J, Pradhan S, Rafferty M, Readinger JL, Whitt AL, Ellis TD. Physical Therapist Management of Parkinson Disease: A Clinical Practice Guideline From the American Physical Therapy Association. Phys Ther. 2022 Apr 1;102(4):pzab302. doi: 10.1093/ptj/pzab302.

MeSH Terms

Conditions

Parkinson Disease

Condition Hierarchy (Ancestors)

Parkinsonian DisordersBasal Ganglia DiseasesBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesMovement DisordersSynucleinopathiesNeurodegenerative Diseases

Study Officials

  • Julie D Ries, PhD

    Marymount University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

June 15, 2023

First Posted

June 26, 2023

Study Start

July 12, 2023

Primary Completion

August 12, 2024

Study Completion

August 12, 2024

Last Updated

August 22, 2024

Record last verified: 2024-08

Data Sharing

IPD Sharing
Will not share

Locations