Outcomes and Efficacy of Ejaculatory Preserving Transurethral Resection of Prostate

NCT05914519 | Completed Results DMC

• 1 other identifier: Soh-Med-23-06-02MD
• Study Type: interventional
• Target: 90
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to assess the outcomes and efficacy of ejaculatory preserving TURP in terms of voiding, erectile function, and ejaculation.

Conditions

Ejaculatory Dysfunction; BPH

Outcome Measures

Primary Outcomes (1)

• Preservation of Ejaculation

  The number of patients who can ejaculate after TURP

  6 months

Secondary Outcomes (1)

• Maximum Flow Rate (Qmax)

  6 months

Study Arms (2)

Group 1

ACTIVE COMPARATOR

Procedure: Ejaculatory Preserving Transurethral resection of prostate

Group 2

ACTIVE COMPARATOR

Procedure: Standard Transurethral Resection of prostate

Interventions

Ejaculatory Preserving Transurethral resection of prostate PROCEDURE

Transurethral resection of prostate with preservation of 1cm safety area above verumontanum and without paracollicular digging

Also known as: EpTURP

Group 1

Standard Transurethral Resection of prostate PROCEDURE

Transurethral resection of prostate including whole adenoma till the capsule.

Also known as: Standard TURP

Group 2

Eligibility Criteria

• Age: 45 Years+
• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Adult patient \> 45 years old.
• Drug refractory urinary retention.
• Prostate volume range: 20-60 mL.
• IPSS \> 19 after the medical therapy failure.
• Qmax \< 10 mL/s.
• PSA \< 4 ng/mL.
• Active and healthy sexual life.

You may not qualify if:

• History of prostate or urethral surgery.
• Neurogenic bladder.
• UTI.
• Urethral stricture disease.
• prostate cancer.
• Bleeding diathesis.
• Capsular or bladder perforation during surgery.

Sponsors & Collaborators

• Sohag University: lead

Study Sites (1)

Sohag University

Sohag, Sohag Governorate, Egypt

Location

MeSH Terms

Conditions

Ejaculatory Dysfunction

Condition Hierarchy (Ancestors)

Genital Diseases, Male; Genital Diseases; Urogenital Diseases; Sexual Dysfunction, Physiological; Male Urogenital Diseases

Limitations and Caveats

* Single center study that may result in different findings than elsewhere. * Small sample size that may produce insignificant results. * Relatively short period of follow-up. * We didn't compare Ejaculatory preserving TURP with other established surgical or minimally invasive techniques such as aquablation and Holmium laser enucleation with ejaculatory sparing modifications.

Results Point of Contact

• Title: Ahmed Sabri mahmoud
• Organization: faculty of medicine sohag university

sabriahmed188@gmail.com

201061691091

Publication Agreements

• PI is Sponsor Employee: Yes

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal investigator

Study Record Dates

• First Submitted: June 12, 2023
• First Posted: June 22, 2023
• Study Start: July 1, 2023
• Primary Completion: January 1, 2025
• Study Completion: June 1, 2025
• Last Updated: January 6, 2026
• Results First Posted: January 6, 2026

Record last verified: 2025-12

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)