Transurethral Resection Versus Transurethral Enucleation of the Prostate: Prospective Randomized Study

NCT05330156 | Unknown

• 1 other identifier: TURP
• Study Type: interventional
• Target: 58
• Locations: 1 country
• Sites: 1

Brief Summary

TUERP technique could be used in prostates of all sizes with the same safety and efficacy "size independent procedure" . TUERP could be performed using the bipolar system only ,with or without the use of morcellator.

Conditions

BPH

Outcome Measures

Primary Outcomes (1)

• Time of operation

  time used for resection or enucleation and resection of the prostate

  intraoperative (from the start of resection or enucleation till the fixation of urethral catheter)

Study Arms (2)

Transurethral resection of the prostate group (TURP).

ACTIVE COMPARATOR

the 1st group of patients will undergone Transurethral resection of the prostate for treatment of BPH

Procedure: Transurethral resection of the prostate

transurethral enucleation of prostate group (TUEP)

ACTIVE COMPARATOR

the 2nd group of patients will undergone Transurethral enucleation of the prostate for treatment of BPH

Procedure: transurethral enucleation of prostate

Interventions

Transurethral resection of the prostate PROCEDURE

\- After an initial cysto-urethroscopy assessment done, Transurethral resection of the prostate is performed using the bipolar system with normal saline irrigation, under spinal or general anesthesia.

Transurethral resection of the prostate group (TURP).

transurethral enucleation of prostate PROCEDURE

After an initial cysto-urethroscopy assessment done, transurethral enucleation of prostate is performed using the bipolar system with normal saline irrigation, under spinal or general anesthesia.

transurethral enucleation of prostate group (TUEP)

Eligibility Criteria

• Gender Eligibility Details: BPH disease is a male disease
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients aging from 50 to 80 years old who are diagnosed with clinical symptomatic BPH.
• The patients have clear indi¬cation for endoscopic surgery (according to the guidelines).
• Clinically fit patients for surgery.
• Signed an informed consent.

You may not qualify if:

• Prostate cancer Previous urethral or prostate surgery Neurogenic bladder Urethral stricture Poor general condition of the patient

Sponsors & Collaborators

• Assiut University: lead

Study Sites (1)

assiut University

Asyut, 71715, Egypt

Location

Related Publications (1)

• Mostafa MM, Ibrahim AF, Moeen AM, Elgammal MA, El-Azab AS, Faragallah MA. Bipolar resection versus enucleation of the prostate in management of benign prostatic hyperplasia patients with large-sized prostates: a prospective randomized controlled clinical trial. BMC Urol. 2026 Jan 24. doi: 10.1186/s12894-025-02004-1. Online ahead of print.

  PMID: 41580733 DERIVED

MeSH Terms

Interventions

Transurethral Resection of Prostate

Intervention Hierarchy (Ancestors)

Prostatectomy; Urologic Surgical Procedures, Male; Urologic Surgical Procedures; Urogenital Surgical Procedures; Surgical Procedures, Operative

Study Officials

• MOHAMED F ABBAS, MD

  AUH

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Ahmed F Hassan, Master

CONTACT

01069569946; ahmedfarahat358@gmail.com

AHMED F HASSAN

CONTACT

01156522620; ahmedfarahat358@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: principal investigator

Study Record Dates

• First Submitted: March 28, 2022
• First Posted: April 15, 2022
• Study Start: April 30, 2022
• Primary Completion: March 30, 2024
• Study Completion: April 30, 2024
• Last Updated: April 15, 2022

Record last verified: 2022-04

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)