NCT05910307

Brief Summary

The purpose of this study is to collect and store data and samples for future research to attempt to improve outcomes for patients with synovial sarcoma. The future research will involve various types of genetic testing. Participants will be asked to allow access to medical records and leftover tumor tissue and may be asked to give a blood or saliva sample. Participants will also be asked to completed questionnaires about their medical history and may be contacted every 6 to 12 months for updates for up to 10 years.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,000

participants targeted

Target at P75+ for all trials

Timeline
84mo left

Started Jun 2023

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress30%
Jun 2023Jun 2033

First Submitted

Initial submission to the registry

June 1, 2023

Completed
11 days until next milestone

Study Start

First participant enrolled

June 12, 2023

Completed
6 days until next milestone

First Posted

Study publicly available on registry

June 18, 2023

Completed
5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2028

Expected
5 years until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2033

Last Updated

June 9, 2026

Status Verified

June 1, 2026

Enrollment Period

5 years

First QC Date

June 1, 2023

Last Update Submit

June 5, 2026

Conditions

Keywords

registrybiorepositorysarcomaoncologycancerrare tumor

Outcome Measures

Primary Outcomes (1)

  • Number of patients with synovial sarcoma

    Number of patients with synovial sarcoma

    Up to 10 years

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Males and females of any age with a reported diagnoses of synovial sarcoma.

You may qualify if:

  • Males or females of any age
  • Reported diagnosis of synovial sarcoma
  • Informed consent from subject (aged ≥18 years) or parent/guardian

You may not qualify if:

  • Individuals with sarcomas that do not fit the definition of those considered for this registry
  • Individuals who are unwilling to participate
  • Individuals who are unwilling or unable to provide written consent

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Children's Hospital of Philadelphia

Philadelphia, Pennsylvania, 19104, United States

RECRUITING

Related Links

Biospecimen

Retention: SAMPLES WITH DNA

Samples may include tumor tissue and its excipients (DNA, RNA, protein), blood, saliva, and/or buccal swabs.

MeSH Terms

Conditions

Sarcoma, SynovialSarcomaNeoplasms

Condition Hierarchy (Ancestors)

Neoplasms, Connective TissueNeoplasms, Connective and Soft TissueNeoplasms by Histologic Type

Study Officials

  • Theodore Laetsch, MD

    Children's Hospital of Philadelphia

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Lauren Gutstein

CONTACT

James Robinson

CONTACT

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
OTHER
Target Duration
10 Years
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 1, 2023

First Posted

June 18, 2023

Study Start

June 12, 2023

Primary Completion (Estimated)

June 1, 2028

Study Completion (Estimated)

June 1, 2033

Last Updated

June 9, 2026

Record last verified: 2026-06

Data Sharing

IPD Sharing
Will share

De-identified data and specimens may be provided to other investigators for additional research use. Identifiable data will only be available to the study team.

Shared Documents
STUDY PROTOCOL, ICF
Time Frame
Upon request, data can be made available after review by study team.
Access Criteria
The study team will review requests on an individual basis.

Locations