Sharing History Through Active Reminiscence and Photo-imagery - With MCI

NCT05906667 | Completed Early Phase 1

• 1 other identifier: 00016980
• Study Type: interventional
• Target: 23
• Locations: 1 country
• Sites: 1

Brief Summary

The SHARP-MCI study tests impact of walking and social reminiscence on cognitive function, blood pressure, and weight among healthy Black Americans and those experiencing mild cognitive impairment (MCI).

Conditions

Cognitive Change

Outcome Measures

Primary Outcomes (1)

• Cognitive function

  Pre/post Montreal Cognitive Assessment

  24 weeks

Secondary Outcomes (2)

• Blood pressure

  24 weeks

• Weight

  24 weeks

Study Arms (1)

Intervention Group

EXPERIMENTAL

All participants assigned to the experimental group (walking)

Behavioral: Sharing History through Active Reminiscence and Photo-imagery (SHARP)

Interventions

Sharing History through Active Reminiscence and Photo-imagery (SHARP) BEHAVIORAL

Participants engage in neighborhood walks and conversational reminisce three times per week over 24 weeks

Also known as: SHARP

Intervention Group

Eligibility Criteria

• Age: 55 Years - 95 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Self-identified African American
• \> 55 years old
• Reside or resided for \>10 years in Portland's historically Black neighborhoods (to be familiar with Memory Markers about this area)
• Able to ambulate independently. Participants (n=7) with MCI will meet criteria consistent with those defined by Jak et al. 2009 and with criteria outlined by the NIA-Alzheimer's Association workgroup (2011)
• Participants without cognitive impairment (n=14) will have an MMSE score \> 24 (and not meet MCI criteria).
• Participants' cognitive function should allow them to get to/ from walk locations independently or with minimal assistance

You may not qualify if:

• Serious or unstable medical condition (such as, but not limited to, cardiovascular disease, pulmonary disease, or severe arthritis) where participation in the trial would, in the opinion of the investigator, pose a significant health risk to the subject.
• Diagnosis of Alzheimer's disease, vascular dementia, Parkinson's disease, or other dementing illness.

Sponsors & Collaborators

• Oregon Health and Science University: lead

Study Sites (1)

Oregon Health & Science University

Portland, Oregon, 97239, United States

Location

Related Publications (2)

• Carder, P., Croff, R., Tuttle, A., Towns, J. (2022) Walking and Talking: Recommendations for Doing Mobile Interviews with Older Adults. Journal of Aging and Environment, DOI: 10.1080/26892618.2022.2030844

  BACKGROUND

• Croff R, Aron S, Wachana A, Fuller P, Mattek N, Towns J, Kaye J. Walking and Social Reminiscence in Gentrifying Neighborhoods: Feasibility and Impact on Cognitive, Physical, and Mental Health Among Older Black Adults in the SHARP Study. Gerontologist. 2024 Sep 1;64(9):gnae019. doi: 10.1093/geront/gnae019.

  PMID: 38412543 DERIVED

Study Design

• Study Type: interventional
• Phase: early phase 1
• Allocation: NA
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: single-arm study; all participants are assigned to the experiment

Study Record Dates

• First Submitted: June 7, 2023
• First Posted: June 18, 2023
• Study Start: May 24, 2017
• Primary Completion: April 30, 2018
• Study Completion: August 30, 2020
• Last Updated: June 18, 2023

Record last verified: 2023-05

Locations

US (1)