Association Between 4-Month Isokinetic Testing Measures and Second Knee Injuries After Primary Anterior Cruciate Ligament Reconstruction

NCT05897970 | Completed

• 1 other identifier: PREDICT-ACLv2
• Study Type: observational
• Target: 150
• Locations: 1 country
• Sites: 1

Brief Summary

Anterior cruciate ligament (ACL) is a frequent and disabling injury in athletes. Most of the time, ACL reconstruction (ACLR) is consider for regaining function and returning to preinjury sports while reducing the risk of secondary injuries. However, the risk of secondary severe knee injury is increased after ACLR, especially in athletes returning to strenuous activities. If strength symmetry is considered as an important factor in the Return-to-sport (RTS) decision, there is conflicting data about the association between strength symmetry and the risk of second knee injury after ACLR. The main objective of this study was to test if knee muscles strength symmetry at 4 months was associated with the psychological readiness and incidence of subsequent severe injury of both knees at a minimum 2 years follow-up after ACL-R.

Conditions

ACL Injury; Knee Injuries; Muscle Weakness

Outcome Measures

Primary Outcomes (1)

• Change in Strength

  Measurement of knee extensors and flexors peak strength (in newton.meter, Nm) on isokinetic dynamometer.

  ACL group: Two evaluations on both injured and healthy knees: 3-4 months after surgery; Routine practice following guidelines]

Secondary Outcomes (4)

• Individual characteristics

  ACLR group: Two follow-up medical consultations: (1) 4 months after surgery and (2) 2 years after the surgery for return to sport and reinjury;

• Surgery characteristics

  ACLR group: Two follow-up medical consultations 4 months after surgery

• Re-injuries

  ACLR group: One evaluation with a minimum 2 years follow-up after the surgery

• Anterior Cruciate Ligament-Return to Sport after Injury (ACL-RSI) scale.

  ACLR group: One evaluation with a minimum 2 years follow-up after the surgery

Study Arms (1)

ACLR patients with Return-to-sport (RTS) follow-up

All sports patients who had a muscle evaluation at 3-4 months after ACLR since January 2017

Diagnostic Test: Return-to-sport (RTS) follow-up

Interventions

Return-to-sport (RTS) follow-up DIAGNOSTIC_TEST

All sports patients who had a muscle evaluation at 3-4 months after ACLR since January 2017

ACLR patients with Return-to-sport (RTS) follow-up

Eligibility Criteria

• Age: 16 Years - 55 Years
• Sex: all
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

All sports patients included in the sport medicine follow-up protocole with isokinetic muscular assessment at 3-4 months after ACL reconstruction surgery since January 2017 with a minium 2 years follow-up in the sports medicine department, Return To Sport Process

You may qualify if:

• Patients who have had an ACL reconstruction surgery (isolated or associated with other meniscal or ligamentary surgery) Patient included in the sport medicine follow-up protocole with intermediate and final isokinetic muscular assessment at 3-4 months Patient who received the information form Patients with access to the Internet

You may not qualify if:

• Patient who did not participate in all follow-up consultations and isokinetic muscular assessments Patients who had a previous knee surgery before the ACLR Cognitive or sensory impairment making it impossible to understand the information form Neurological, traumatic or osteoarticular history responsible for muscle imbalance prior to surgery

Sponsors & Collaborators

• University Hospital, Caen: lead

Study Sites (1)

CHU Caen Normandie

Caen, 14000, France

Location

MeSH Terms

Conditions

Anterior Cruciate Ligament Injuries; Knee Injuries; Muscle Weakness

Condition Hierarchy (Ancestors)

Leg Injuries; Wounds and Injuries; Muscular Diseases; Musculoskeletal Diseases; Neuromuscular Manifestations; Neurologic Manifestations; Nervous System Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 1, 2023
• First Posted: June 12, 2023
• Study Start: May 1, 2021
• Primary Completion: May 1, 2021
• Study Completion: May 1, 2023
• Last Updated: March 26, 2025

Record last verified: 2023-06

Locations

FR (1)