NCT05896722

Brief Summary

Every individual with joint hypermobility may not apply to a health institution because they do not have a complaint that will affect their daily life. Although hypermobility is a common clinical entity in the society, this issue has not been fully understood yet. In particular, individuals with GJH are either neglected in physiotherapy and rehabilitation evaluations and practices, or they encounter an incomplete assessment and physiotherapy practices. In this study, in order to better understand the effect of GJH on "core" muscle endurance, upper extremity strength, grip strength and coordination, we will include the individuals identified GJH among the university students (hypermobility severity ≥4/9 according to Beighton diagnostic criteria) as study group and the healthy peers as control group. We believe the results we will obtain at the end of our study will make a contribution to the literature in terms of revealing the role of "core" muscle endurance and upper extremity strength, grip strength and coordination in the evaluation and rehabilitation of individuals with GJH. In addition, it will contribute to the inclusion of individuals with GJH who are professional athletes, dancers or musicians in a more comprehensive evaluation program and the creation of physiotherapy and rehabilitation programs. According to the information we have obtained from the literature, it is a fact that hypermobility can increase the susceptibility to musculoskeletal system diseases. For this reason, early solutions to problems can be provided by evaluating hypermobility in patients who apply to health institutions with various musculoskeletal complaints, raising awareness of patients with hypermobility to prevent injuries caused by hypermobility, and strengthening muscles.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
54

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Apr 2023

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 25, 2023

Completed
13 days until next milestone

First Submitted

Initial submission to the registry

May 8, 2023

Completed
1 month until next milestone

First Posted

Study publicly available on registry

June 9, 2023

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2023

Completed
17 days until next milestone

Study Completion

Last participant's last visit for all outcomes

September 18, 2023

Completed
Last Updated

September 21, 2023

Status Verified

September 1, 2023

Enrollment Period

4 months

First QC Date

May 8, 2023

Last Update Submit

September 18, 2023

Conditions

Outcome Measures

Primary Outcomes (2)

  • Alternate hand-wall toss test

    To measure hand-eye coordination, it is performed by changing hands by throwing and catching the ball against the wall. The action is repeated for a period of 30 seconds.

    One day

  • Core muscle endurance tests

    Trunk flexion, trunk extension, side bridge exercises and prone bridge test developed by McGill will be used to evaluate core muscle endurance.

    One day

Secondary Outcomes (3)

  • Upper extremity muscle strength measurement

    One day

  • Grip strength measurement

    One day

  • Pinch strength measurement

    One day

Study Arms (2)

Study group

27 young adults aged 17-26 who scored 4 or more according to the Beighton scoring

Other: Core muscle enduranceOther: Upper extremity muscle strengthOther: Grip strengthOther: Pinch strengthOther: Alternate hand-wall toss test

Control group

27 young adults aged 17-26 who scored less than 4 points according to the Beighton scoring

Other: Core muscle enduranceOther: Upper extremity muscle strengthOther: Grip strengthOther: Pinch strengthOther: Alternate hand-wall toss test

Interventions

Trunk flexion, trunk extension, side bridge exercises and prone bridge test developed by McGill will be used to evaluate core muscle endurance.

Control groupStudy group

Isometric muscle strength assessment of the shoulder, elbow and wrist muscles will be performed with a hand-held dynamometer.

Control groupStudy group

Grip strength will be evaluated with a hand dynamometer in the position recommended by the American Association of Hand Therapists.

Control groupStudy group

Pinch strength will be evaluated with a pinchmeter in three positions.

Control groupStudy group

To measure hand-eye coordination, it is performed by changing hands by throwing and catching the ball against the wall.

Control groupStudy group

Eligibility Criteria

Age17 Years - 26 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64)
Sampling MethodProbability Sample
Study Population

Young adults between the ages of 17-26 years with a score of 4 or higher according to the Beighton criteria.

You may qualify if:

  • Getting a score of 4 or higher according to the Beighton criteria
  • Being between the ages of 17-26

You may not qualify if:

  • Presence of benign joint hypermobility syndrome
  • Presence of any neurological, rheumatic, musculoskeletal, metabolic and connective tissue disease
  • History of fracture in the upper extremity
  • History of pain, deformity or surgery associated with the vertebral column and upper extremity
  • Presence of cognitive, mental and/or serious psychiatric illness
  • Participating in any exercise program or sportive activity in the last six months

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Bezmialem Vakif University

Istanbul, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Joint InstabilityMuscle WeaknessAtaxia

Interventions

Hand StrengthPinch Strength

Condition Hierarchy (Ancestors)

Joint DiseasesMusculoskeletal DiseasesMuscular DiseasesNeuromuscular ManifestationsNeurologic ManifestationsNervous System DiseasesPathologic ProcessesPathological Conditions, Signs and SymptomsSigns and SymptomsDyskinesias

Intervention Hierarchy (Ancestors)

Muscle StrengthPhysical ExaminationDiagnostic Techniques and ProceduresDiagnosisMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Study Officials

  • Deniz Tuncer, PhD, PT

    Bezmialem Vakif University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
CROSS SECTIONAL
Target Duration
1 Day
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant professor

Study Record Dates

First Submitted

May 8, 2023

First Posted

June 9, 2023

Study Start

April 25, 2023

Primary Completion

September 1, 2023

Study Completion

September 18, 2023

Last Updated

September 21, 2023

Record last verified: 2023-09

Locations