Exploring the Changes of Inflammatory Factors in Joint Fluid of Patients With Sports Injury for 1-year Postoperative Rehabilitation and Clinical Treatment
1 other identifier
observational
200
1 country
1
Brief Summary
This study intends to use a prospective study design method to continuously collect immune cell and inflammatory factor data of 5ml peripheral blood and 10ml joint fluid from 200 patients who met the inclusion and exclusion criteria in our department from January 2020 to January 2022. The aim is to analyze the impact of changes in inflammatory factors before and after surgery on postoperative recovery.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jan 2021
Typical duration for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 31, 2021
CompletedFirst Submitted
Initial submission to the registry
May 27, 2023
CompletedFirst Posted
Study publicly available on registry
June 8, 2023
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 28, 2023
CompletedStudy Completion
Last participant's last visit for all outcomes
December 28, 2023
CompletedJune 8, 2023
May 1, 2023
2.9 years
May 27, 2023
June 7, 2023
Conditions
Outcome Measures
Primary Outcomes (3)
Visual Analog Score for pain (VAS)
The VAS scale mainly evaluates the postoperative pain score of patients, with values ranging from 0 to 10. The higher the value, the more severe the pain;
Change from 2 weeks, 1 month, 3 months, 6 months, and 1 Year after ACLR operation
Lysholm score
The Lysholm scale mainly evaluates the postoperative recovery of knee joint function in patients, with values ranging from 0 to 100. The higher the value, the better the recovery;
Change from 6 months and 1 Year after ACLR operation
Tegner sacle
The Tegner scale is also mainly used to evaluate the postoperative recovery of knee joint function in patients, with values ranging from 0 to 10. The higher the value, the better the recovery
Change from 6 months and 1 Year after ACLR operation
Eligibility Criteria
Patients who underwent anterior cruciate ligament reconstruction surgery at the Sports Medicine Department of Sun Yat sen Memorial Hospital and required joint effusion extraction due to postoperative treatment
You may qualify if:
- Those with healthy diet and regular exercise habits;
- Sports injury patients(Satisfy one of the following conditions): Anterior cruciate ligament injury or meniscus injury
You may not qualify if:
- Existence of underlying diseases related to the immune system;
- Trauma leading to knee joint fracture;
- Blood pressure, heart rate, vital capacity, muscle tension and other indicators are obviously abnormal;
- Significant abnormalities in blood routine, infection indicators, heart, lung, liver, and kidney function tests, insufficient compensatory function of important organs, or severe systemic diseases;
- Patients with neurological or psychiatric disorders, pregnant women, or a history of related illnesses combined with severe organic diseases
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Sun Yatsen Memorial Hospital
Guangzhou, Guangdong, 510120, China
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
May 27, 2023
First Posted
June 8, 2023
Study Start
January 31, 2021
Primary Completion
December 28, 2023
Study Completion
December 28, 2023
Last Updated
June 8, 2023
Record last verified: 2023-05