Ultrasound Evaluation of Hamstring Tendon Regeneration After ACL Reconstruction and Its Influence
1 other identifier
observational
110
1 country
1
Brief Summary
High incidence rate of knee osteoarthritis and gait analysis are important for early assessment of biomechanics. ACL injury is an ideal clinical model for studying knee osteoarthritis. To clarify the mechanism between the biomechanical status of knee joint and the change of gait touch information, and to provide scientific basis for quantifying and evaluating the biomechanical status of knee joint in dynamic load-bearing state.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Feb 2018
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
February 2, 2018
CompletedPrimary Completion
Last participant's last visit for primary outcome
January 8, 2020
CompletedFirst Submitted
Initial submission to the registry
June 29, 2020
CompletedFirst Posted
Study publicly available on registry
July 14, 2021
CompletedStudy Completion
Last participant's last visit for all outcomes
December 31, 2022
CompletedJuly 14, 2021
July 1, 2020
1.9 years
June 29, 2020
July 4, 2021
Conditions
Keywords
Outcome Measures
Primary Outcomes (67)
peak ground reaction force
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
On the day of enrollment.
peak ground reaction force
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
At 3 months after Anterior Cruciate Ligament reconstruction.
peak ground reaction force
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
At 6 months after Anterior Cruciate Ligament reconstruction.
peak ground reaction force
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
At 12 months after Anterior Cruciate Ligament reconstruction.
peak ground reaction force
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
At 24 months after Anterior Cruciate Ligament reconstruction.
angle of hip in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
At 24 months after Anterior Cruciate Ligament reconstruction.
angle of hip in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
On the day of enrollment.
angle of hip in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
At 3 months after Anterior Cruciate Ligament reconstruction.
angle of hip in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
At 6 months after Anterior Cruciate Ligament reconstruction.
angle of hip in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
At 12 months after Anterior Cruciate Ligament reconstruction.
bilateral knee extension torque
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
On the day of enrollment.
bilateral knee extension torque
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
At 3 months after Anterior Cruciate Ligament reconstruction.
bilateral knee extension torque
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
At 6 months after Anterior Cruciate Ligament reconstruction.
bilateral knee extension torque
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
At 12 months after Anterior Cruciate Ligament reconstruction.
bilateral knee extension torque
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
At 24 months after Anterior Cruciate Ligament reconstruction.
knee flexion torque at different angles
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
On the day of enrollment.
knee flexion torque at different angles
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
At 3 months after Anterior Cruciate Ligament reconstruction.
knee flexion torque at different angles
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
At 6 months after Anterior Cruciate Ligament reconstruction.
knee flexion torque at different angles
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
At 12 months after Anterior Cruciate Ligament reconstruction.
knee flexion torque at different angles
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
At 24 months after Anterior Cruciate Ligament reconstruction.
angular velocities
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
On the day of enrollment.
angular velocities
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
At 3 months after Anterior Cruciate Ligament reconstruction.
angular velocities
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
At 6 months after Anterior Cruciate Ligament reconstruction.
angular velocities
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
At 12 months after Anterior Cruciate Ligament reconstruction.
angular velocities
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
At 24 months after Anterior Cruciate Ligament reconstruction.
the thickness of the semitendinosus
Ultrasound evaluation was made by Ultrasonic detector.
On the day of enrollment.
the cross-sectional area of the semitendinosus
Ultrasound evaluation was made by Ultrasonic detector.
On the day of enrollment.
the thickness of the semitendinosus
Ultrasound evaluation was made by Ultrasonic detector.
At 2 weeks after Anterior Cruciate Ligament reconstruction.
the cross-sectional area of the semitendinosus
Ultrasound evaluation was made by Ultrasonic detector.
At 2 weeks after Anterior Cruciate Ligament reconstruction.
the thickness of the semitendinosus
Ultrasound evaluation was made by Ultrasonic detector.
At 3 months after Anterior Cruciate Ligament reconstruction.
the cross-sectional area of the semitendinosus
Ultrasound evaluation was made by Ultrasonic detector.
At 3 months after Anterior Cruciate Ligament reconstruction.
the thickness of the semitendinosus
Ultrasound evaluation was made by Ultrasonic detector.
At 6 months after Anterior Cruciate Ligament reconstruction.
the cross-sectional area of the semitendinosus
Ultrasound evaluation was made by Ultrasonic detector.
At 6 months after Anterior Cruciate Ligament reconstruction.
the thickness of the semitendinosus
Ultrasound evaluation was made by Ultrasonic detector.
At 12 months after Anterior Cruciate Ligament reconstruction.
the cross-sectional area of the semitendinosus
Ultrasound evaluation was made by Ultrasonic detector.
At 12 months after Anterior Cruciate Ligament reconstruction.
the thickness of the semitendinosus
Ultrasound evaluation was made by Ultrasonic detector.
At 24 months after Anterior Cruciate Ligament reconstruction.
the cross-sectional area of the semitendinosus
Ultrasound evaluation was made by Ultrasonic detector.
At 24 months after Anterior Cruciate Ligament reconstruction.
shear wave velocity of the semitendinosus
Ultrasound evaluation was made by Ultrasonic detector.
On the day of enrollment.
shear wave velocity of the semitendinosus
Ultrasound evaluation was made by Ultrasonic detector.
At 3 months after Anterior Cruciate Ligament reconstruction.
shear wave velocity of the semitendinosus
Ultrasound evaluation was made by Ultrasonic detector.
At 6 months after Anterior Cruciate Ligament reconstruction.
shear wave velocity of the semitendinosus
Ultrasound evaluation was made by Ultrasonic detector.
At 12 months after Anterior Cruciate Ligament reconstruction.
shear wave velocity of the semitendinosus
Ultrasound evaluation was made by Ultrasonic detector.
At 24 months after Anterior Cruciate Ligament reconstruction.
torque of hip, knee and ankle joints in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
At 24 months after Anterior Cruciate Ligament reconstruction.
torque of hip, knee and ankle joints in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
On the day of enrollment.
torque of hip, knee and ankle joints in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
At 3 months after Anterior Cruciate Ligament reconstruction.
torque of hip, knee and ankle joints in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
At 6 months after Anterior Cruciate Ligament reconstruction.
torque of hip, knee and ankle joints in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
At 12 months after Anterior Cruciate Ligament reconstruction.
angle of knee joints in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
On the day of enrollment.
angle of knee joints in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
At 3 months after Anterior Cruciate Ligament reconstruction.
angle of knee joints in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
At 6 months after Anterior Cruciate Ligament reconstruction.
angle of knee joints in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
At 12 months after Anterior Cruciate Ligament reconstruction.
angle of knee joints in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
At 24 months after Anterior Cruciate Ligament reconstruction.
angle of ankle joints in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
On the day of enrollment.
angle of ankle joints in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
At 3 months after Anterior Cruciate Ligament reconstruction.
angle of ankle joints in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
At 6 months after Anterior Cruciate Ligament reconstruction.
angle of ankle joints in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
At 12 months after Anterior Cruciate Ligament reconstruction.
angle of ankle joints in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
At 24 months after Anterior Cruciate Ligament reconstruction.
torque of knee joints in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
On the day of enrollment.
torque of knee joints in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
At 3 months after Anterior Cruciate Ligament reconstruction.
torque of knee joints in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
At 6 months after Anterior Cruciate Ligament reconstruction.
torque of knee joints in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
At 12 months after Anterior Cruciate Ligament reconstruction.
torque of knee joints in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
At 24 months after Anterior Cruciate Ligament reconstruction.
torque of ankle joints in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
On the day of enrollment.
torque of ankle joints in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
At 3 months after Anterior Cruciate Ligament reconstruction.
torque of ankle joints in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
At 6 months after Anterior Cruciate Ligament reconstruction.
torque of ankle joints in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
At 12 months after Anterior Cruciate Ligament reconstruction.
torque of ankle joints in different stages
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping.
At 24 months after Anterior Cruciate Ligament reconstruction.
Secondary Outcomes (1)
The International Knee Documentation Committee (IKDC) score
On the day of enrollment, at 3 months, 6 months, 12 months after operation and 24 months after Anterior Cruciate Ligament reconstruction.
Study Arms (2)
Anterior Cruciate Ligament injury and reconstruction group
According to the previous clinical diagnosis, volunteers who has never suffered the Anterior Cruciate Ligament injury.
normal control group
According to the previous clinical diagnosis, volunteers who has never suffered the lower extremity sports injuries.
Interventions
This is an observation study, with no intervention
Eligibility Criteria
Inclusion criteria: Age: 18-35 years old. Patients who have isolated ACL injury and receive ACL reconstruction surgery at Peking University Third Hospital. With isolated ACL injury (an ACL injury with no need for surgical repairs to other knee structures). All participants have no known disorders or diseases other than ACL rupture. Exclusion criteria: Female patients who are pregnant, or suspected pregnant, or in breastfeeding will be excluded from this study.
You may qualify if:
- years old
- Patients who have isolated ACL injury and receive ACL reconstruction surgery at Peking University Third Hospital.
- With isolated ACL injury (an ACL injury with no need for surgical repairs to other knee structures).
- All participants have no known disorders or diseases other than ACL rupture.
You may not qualify if:
- Female patients who are pregnant, or suspected pregnant, or in breastfeeding will be excluded from this study.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Peking University Third Hospital
Beijing, 100191, China
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY CHAIR
Hongshi Huang, Doctor
Peking University Third Hospital
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
June 29, 2020
First Posted
July 14, 2021
Study Start
February 2, 2018
Primary Completion
January 8, 2020
Study Completion
December 31, 2022
Last Updated
July 14, 2021
Record last verified: 2020-07
Data Sharing
- IPD Sharing
- Will not share