Frailty in the Perioperative Period

NCT05893342 | Recruiting

• 1 other identifier: 2019-343-1
• Study Type: observational
• Target: 138
• Locations: 1 country
• Sites: 1

Brief Summary

The presence of frailty is associated with a high risk of complications in the perioperative period, increasing morbidity and mortality, hospital stay, and loss of quality of life. In this prospective observational study, an evaluation of frailty was performed in patients older than 65 years old who undergo scheduled and urgent surgery. 138 patients are being included. The main objective is to evaluate the prevalence of frailty in patients older than 65 years undergoing surgery in our hospital and its association with postoperative mortality.

Conditions

Frailty

Keywords

Preoperative frailty; Postoperative complications

Outcome Measures

Primary Outcomes (2)

• Prevalence of frailty

  Prevalence of frailty in patients older than 65 years undergoing surgery in our hospital

  First preoperative day

• Postoperative complications

  Relationship of preoperative frailty in patients older than 65 years undergoing surgery in our hospital and postoperative mortality

  90 postoperative days

Secondary Outcomes (2)

• Postoperative evolution

  90 postoperative days

• Functional independence

  First postoperative year

Interventions

Preoperative frailty diagnostic DIAGNOSTIC_TEST

The preoperative evaluation of the patient will be carried out through the application of different scales that evaluate frailty (Edmonton frailty test, Barthel Index, Mini-mental test, Charlson Index) and a postoperative follow-up will be carried out for the diagnosis of complications during the first 90 postoperative days.

Eligibility Criteria

• Age: 65 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

All patients over 65 years old undergoing surgery will be visited 24 hours before the intervention to sign the informed consent and the preoperative evaluation will be carried out through the application of different scales that evaluate the frailty of the patient. The patient will be monitored from his admission to the hospital until discharge and up to 3 months after the day of surgery. Data will be collected on in-hospital complications (medical or surgical), days of hospital stay, unforeseen need for ICU admission, if there has been loss of instrumental or cognitive abilities, and in-hospital mortality data and up to 3 months after surgery.

You may qualify if:

• Patients over 65 years old undergoing urgent or scheduled surgery

You may not qualify if:

• Language barrier
• Cognitive impairment or inability to assist in clinical assessment during the study
• Refusal to participate in the study

Sponsors & Collaborators

• Dr. Negrin University Hospital: lead
• University of Las Palmas de Gran Canaria: collaborator

Study Sites (1)

Ángel Becerra

Las Palmas de Gran Canaria, Las Palmas, 35019, Spain

RECRUITING

MeSH Terms

Conditions

Frailty; Postoperative Complications

Condition Hierarchy (Ancestors)

Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Ángel Becerra, PhD

  Hospital Universitario de Gran Canaria Doctor Negrín

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Ángel Becerra, PhD

CONTACT

+34676229025; angbecbol@gmail.com

Aurelio Rodriguez-Pérez, PhD

CONTACT

+34928450371; arodperp@gobiernodecanarias.org

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: May 29, 2023
• First Posted: June 7, 2023
• Study Start: March 1, 2024
• Primary Completion: September 30, 2025
• Study Completion: September 30, 2025
• Last Updated: August 24, 2025

Record last verified: 2025-08

Locations

ES (1)