NCT05890378

Brief Summary

The main objective of this study is to determine the effectiveness of a livestock management intervention, with considerations for animal food security, water contamination from animals, and nutrition counseling, in reducing the risk of acute malnutrition among children under the age of 5 years in Kanem and Bahr El Ghazel (BeG) in Chad.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
15,000

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jul 2023

Typical duration for all trials

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 25, 2023

Completed
12 days until next milestone

First Posted

Study publicly available on registry

June 6, 2023

Completed
25 days until next milestone

Study Start

First participant enrolled

July 1, 2023

Completed
2.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2026

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2026

Completed
Last Updated

June 7, 2023

Status Verified

June 1, 2023

Enrollment Period

2.6 years

First QC Date

May 25, 2023

Last Update Submit

June 6, 2023

Conditions

Keywords

malnutrition

Outcome Measures

Primary Outcomes (1)

  • Water Quality

    Water quality: total coliform and E. coli

    2023-2026

Study Arms (1)

Cohort by Water Source

Using existing secondary data available on the research communities as well as qualitative inquiry, we will purposefully select 40 water sources for the water analysis across from the communities selected for the implementation research (up to 30 communities with a maximum of 5 water sources per community). The selection of water sources will be stratified by type of water sourceand near the route for long-term animal migration. For each water source, we will aim to have a water sample collected at all water sources twice a day (morning and later afternoon) once a week for four weeks, varying the day of the week. Thus, we will collect a total of 320 water samples in the course of four weeks at the end of the dry season before the rains start.

Other: Testing water

Interventions

Using existing secondary data available on the research communities as well as qualitative inquiry, we will purposefully select 40 water sources for the water analysis across from the communities selected for the implementation research (up to 30 communities with a maximum of 5 water sources per community). The selection of water sources will be stratified by type of water sourceand near the route for long-term animal migration. For each water source, we will aim to have a water sample collected at all water sources twice a day (morning and later afternoon) once a week for four weeks, varying the day of the week. Thus, we will collect a total of 320 water samples in the course of four weeks at the end of the dry season before the rains start.

Cohort by Water Source

Eligibility Criteria

Age6 Months - 5 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)
Sampling MethodNon-Probability Sample
Study Population

Although the final target for many nutrition messages will be women with young children, their ability to carry out promoted practices depends on the influence and control of a range of actors. Likewise, both men and women in households with livestock make decisions that affect resources provided to milking animals and access to milk - and these individuals are affected by a range of other actors in the community.

You may qualify if:

  • Communities selected for the research have to be near a seasonal river
  • Households (within those communities) have to have at least one child between the ages of 6 and 59 months.
  • Households (within those communities) have to have at least one Tropical Livestock Unit (TLU) of livestock. One TLU is equivalent to either one cow, one camel, 10 goats or 10 sheep.
  • Within those households, we will interview the female caretaker
  • Anthropometry data will be collected from children 6-59 months and the female caretaker

You may not qualify if:

  • lack of children under 5 years of age and/or a required livestock unit

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Biospecimen

Retention: SAMPLES WITH DNA

fecal matter

MeSH Terms

Conditions

Child Nutrition DisordersMalnutrition

Condition Hierarchy (Ancestors)

Nutrition DisordersNutritional and Metabolic Diseases

Central Study Contacts

Anastasia Marshak, PhD

CONTACT

Anna Ronell, PhD

CONTACT

Study Design

Study Type
observational
Observational Model
ECOLOGIC OR COMMUNITY
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 25, 2023

First Posted

June 6, 2023

Study Start

July 1, 2023

Primary Completion

February 1, 2026

Study Completion

February 1, 2026

Last Updated

June 7, 2023

Record last verified: 2023-06

Data Sharing

IPD Sharing
Will not share