NCT05875857

Brief Summary

This is a study on how patients use and store opioid pain medications at home after surgery and what happens to left over pills when patients are done taking them. Participants will be taught the proper storage and destruction of opioid pain medications, then contacted in 6-8 weeks about pain medication used, stored disposed of.

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
163

participants targeted

Target at P75+ for not_applicable

Timeline
8mo left

Started Jun 2023

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress82%
Jun 2023Jan 2027

First Submitted

Initial submission to the registry

May 4, 2023

Completed
21 days until next milestone

First Posted

Study publicly available on registry

May 25, 2023

Completed
25 days until next milestone

Study Start

First participant enrolled

June 19, 2023

Completed
1.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 31, 2025

Completed
1.8 years until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2027

Expected
Last Updated

January 29, 2026

Status Verified

January 1, 2026

Enrollment Period

1.8 years

First QC Date

May 4, 2023

Last Update Submit

January 27, 2026

Conditions

Opioid UseOpioid Use, UnspecifiedPatient EmpowermentTotal Knee ArthoplastyTotal Hip Arthroplasty

Outcome Measures

Primary Outcomes (1)

  • Opioid destruction

    Number of patients who report they did or plan to destroy unused opioids

    Six to Eight weeks post discharge

Secondary Outcomes (4)

  • Patient Education

    Six to Eight weeks post discharge

  • Opioid Storage

    Six to Eight weeks post discharge

  • Opioid Destruction Method

    Six to Eight weeks post discharge

  • Leftover Pills

    Six to Eight weeks post discharge

Study Arms (2)

Control

NO INTERVENTION

Control group will receive current standard of care education and surveys at 6-8 weeks post discharge.

Intervention

EXPERIMENTAL

Intervention group will receive a specialized handout and patient education on the safe storage of opioid medications, importance of opioid destruction, opioid destruction options and medication destruction (Deterra) bag before discharge. Surveys will be sent to group at 6-8 weeks post discharge.

Behavioral: Opioid destruction education

Interventions

Opioid destruction educationBEHAVIORAL

Intervention group will receive a specialized handout and patient education on the safe storage of opioid medications, importance of opioid destruction, opioid destruction options and medication destruction (Deterra) bag before discharge.

Intervention

Eligibility Criteria

Age19 Years - 100 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • years of age or older Discharging to home and prescribed opioids at discharge post total knee arthroplasty or total hip arthroplasty

You may not qualify if:

  • Under 19 years of age Opioid medication use prior to surgery Not prescribed an opioid to take after discharge

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Nebraska Medical Center

Omaha, Nebraska, 68198, United States

Location

MeSH Terms

Conditions

Patient Participation

Condition Hierarchy (Ancestors)

Patient Acceptance of Health CareTreatment Adherence and ComplianceHealth BehaviorBehavior

Study Officials

  • Kristin R Daniel, PharmD

    University of Nebraska

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 4, 2023

First Posted

May 25, 2023

Study Start

June 19, 2023

Primary Completion

March 31, 2025

Study Completion (Estimated)

January 1, 2027

Last Updated

January 29, 2026

Record last verified: 2026-01

Data Sharing

IPD Sharing
Will not share

Locations

US(1)