A Multicenter Observational Cohort of Degenerative Spine Diseases in China（DSDC）

NCT05867732 | Completed

• 1 other identifier: XiamenUDSDC
• Study Type: observational
• Target: 10,000
• Locations: 1 country
• Sites: 1

Brief Summary

Study type: The objectives of this observational study were to understand, analyze, and compare the treatment and prognosis of patients with degenerative spine diseases and to construct a risk warning model and an assisted decision-making system The main questions it aims to answer are:

• \[question 1\] to construct a database of patients with degenerative spinal diseases and to study their associated prognosis, complications, and other risks
• \[Question 2\] Use big data to build a risk early warning model and assisted decision making system The study will not intervene with patients

Conditions

Degenerative Spine Diseases

Outcome Measures

Primary Outcomes (1)

• Collect demographics (Hospital Information System)

  Collect demographics from the HIS system for patients with degenerative spine disease

  2022.03

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with degenerative spine disease (lumbar disc herniation, lumbar spinal stenosis, lumbar spondylolisthesis, scoliosis deformity, etc.) seen and treated in participating units between January 2015 and January 2022, excluding patients with neoplastic disease

You may qualify if:

• patients with degenerative spine disease admitted to the units participating in the study from January 2015 to mid-January 2022;
• complete patient data with no more than 5% missing;

You may not qualify if:

• Patients with oncology;

Sponsors & Collaborators

• Xiamen University: lead

Study Sites (1)

Wenle Li

Xianmencun, 361102, China

Location

Related Publications (2)

• Shen N, Zhang Y, Ding Z, Li R, Quan X, Liu X, Zhang Y, Xiang T, Zhang Y, Yin C, Li W. Predicting intraoperative blood loss risk in severe lumbar disc herniation patients undergoing PLIF: a multicenter cohort study using ensemble learning. Int J Surg. 2025 Sep 1;111(9):5904-5913. doi: 10.1097/JS9.0000000000002730. Epub 2025 Jun 19.

  PMID: 40540437 DERIVED

• Li W, Zhang Y, Zhou X, Quan X, Chen B, Hou X, Xu Q, He W, Chen L, Liu X, Zhang Y, Xiang T, Li R, Liu Q, Wu SN, Wang K, Liu W, Zheng J, Luan H, Yu X, Chen A, Xu C, Luo T, Hu Z. Ensemble learning-assisted prediction of prolonged hospital length of stay after spine correction surgery: a multi-center cohort study. J Orthop Surg Res. 2024 Feb 2;19(1):112. doi: 10.1186/s13018-024-04576-4.

  PMID: 38308336 DERIVED

Study Officials

• Wenle Wenle, M.D.

  Xiamen University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: OTHER
• Target Duration: 1 Year
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Dr.

Study Record Dates

• First Submitted: May 11, 2023
• First Posted: May 22, 2023
• Study Start: March 1, 2022
• Primary Completion: March 10, 2022
• Study Completion: March 1, 2023
• Last Updated: May 22, 2023

Record last verified: 2023-05

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)