Neutrophil/Lymphocyte Ratio in Acute Pancreatitis

NCT05859633 | Unknown

• 1 other identifier: Romay
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

Acute pancreatitis (AP) is a disease characterized by dysfunction of pancreatic acinar cells, improper activation of trypsin, and subsequent destruction of pancreatic self-defense mechanisms, further exacerbating injury and damage of pancreatic cells. It is a rapidly developing inflammatory process of the pancreas, and the most common reasons are alcohol and gallstones.

Conditions

Acute Pancreatitis

Outcome Measures

Primary Outcomes (1)

• severe acute pancreatitis

  frequency of severe acute pancreatitis

  one year

Study Arms (1)

patients with acute pancreatitis

any patient suffers from acute pancreatitis

Diagnostic Test: Neutrophil/Lymphocyte Ratio in acute pancreatitis

Interventions

Neutrophil/Lymphocyte Ratio in acute pancreatitis DIAGNOSTIC_TEST

role of Neutrophil/Lymphocyte Ratio in acute pancreatitis

patients with acute pancreatitis

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Any patient who is above age of 18 years old and diagnosed to have AP. Patients were diagnosed with acute pancreatitis if more than 2 of the following conditions were satisfied: 1) abdominal pain consistent with acute pancreatitis (acute onset of a persistent, severe, epigastric pain often radiating to the back); 2) serum amylase and/or lipase level at least 3 times greater than the upper limit of the normal value; and 3) characteristic manifestation of acute pancreatitis on contrast-enhanced computed tomography, magnetic resonance imaging, or transabdominal ultrasonography

You may qualify if:

• patients with acute pancreatitis

You may not qualify if:

• Patients with acute abdomen with diagnosis other than AP
• Patients with AP who are under age of 18 years old
• Patient's refusal

Sponsors & Collaborators

• Assiut University: lead

Study Sites (1)

Ahmed Mohammed Abu-Elfatth

Asyut, 71515, Egypt

RECRUITING

Related Publications (1)

• Mederos MA, Reber HA, Girgis MD. Acute Pancreatitis: A Review. JAMA. 2021 Jan 26;325(4):382-390. doi: 10.1001/jama.2020.20317.

  PMID: 33496779 BACKGROUND

MeSH Terms

Conditions

Pancreatitis

Condition Hierarchy (Ancestors)

Pancreatic Diseases; Digestive System Diseases

Study Officials

• Ahmed M Abu-Elfatth

  Assiut University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Ahmed M Abu-Elfatth

CONTACT

+18677791; ahmed111@aun.edu.eg

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Internal Medicine

Study Record Dates

• First Submitted: May 4, 2023
• First Posted: May 16, 2023
• Study Start: May 30, 2023
• Primary Completion: December 30, 2023
• Study Completion: December 31, 2023
• Last Updated: May 16, 2023

Record last verified: 2023-05

Locations

EG (1)