Prevalence of Echocardioghraphic and ECG Changes in Patients With Acute Pancreatitis and Its Impact on Outcome.

NCT04196504 | Unknown

• 1 other identifier: Echo_ECG_pancreatitis
• Study Type: observational
• Target: 30
• Locations: 0 countries
• Sites: N/A

Brief Summary

Cardiovascular system involvement with acute pancreatitis has been described before in the form of ECG changes and echocardiographic findings. However the correlation between these changes and the outcome of acute pancreatitis has not been and whether they can be used to predict mortality in these patients has been controversial.In the current study our aim is to detect echocardioghraphic and ECG changes in acute pancreatitis and investigate the significance of these changes on prognosis.

Conditions

Acute Pancreatitis

Outcome Measures

Primary Outcomes (2)

• Echocardiographic (mainly diastolic dysfunction & pericardial effusion) and ECG changes (mainly QT interval) in patients with acute pancreatitis.

  To detect the echocardiographic (mainly diastolic dysfunction \& pericardial effusion) and ECG changes (mainly QT interval) in patients with acute pancreatitis.

  at admission on 1st day

• determine the impact of these changes on outcome of patients

  determine the impact of these changes on outcome of patients

  though out hospital admission (an average of 1 week)

Interventions

Echocardiograghy, ECG DEVICE

transthoracic echocariography, 12 lead ECG

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

all patients with acute pancreatitis aged more than 18 yrs \& less than 80 years old not known cardiac and with no pre-existing diabetes, chronic renal failure or malignancy with no hx of chronic pancreatitis admitted to Al-raghy ICU of all etiologies

You may qualify if:

• all patients with acute pancreatitis aged more than 18 yrs admitted to Al-raghy ICU of all etiologies

You may not qualify if:

• patients less that 18 years
• patients above 80 years
• patients with known cardiac disease
• patients with pre-existing diabetes, chronic renal failure or malignancy.
• patients with underlying chronic pancreatitis

Sponsors & Collaborators

• Assiut University: lead

MeSH Terms

Conditions

Pancreatitis

Interventions

Electrocardiography

Condition Hierarchy (Ancestors)

Pancreatic Diseases; Digestive System Diseases

Intervention Hierarchy (Ancestors)

Heart Function Tests; Diagnostic Techniques, Cardiovascular; Diagnostic Techniques and Procedures; Diagnosis; Electrodiagnosis

Study Officials

• Mahmoud Ashry, professor

  Assiut University

  STUDY CHAIR

• Lobna Abdelwahid, assistant professor

  Assiut University

  STUDY DIRECTOR

Central Study Contacts

Alaaeldin M. Abdelrahman, MBBS

CONTACT

01144780935; aladdinmahmoud@yahoo.com

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: October 12, 2019
• First Posted: December 12, 2019
• Study Start: December 31, 2019
• Primary Completion: December 31, 2021
• Study Completion: December 31, 2021
• Last Updated: December 12, 2019

Record last verified: 2019-12