NCT05850975

Brief Summary

This study investigates the short-term effects of the MindEase app on anxiety levels.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
6,200

participants targeted

Target at P75+ for not_applicable anxiety

Timeline
Completed

Started Apr 2023

Shorter than P25 for not_applicable anxiety

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 11, 2023

Completed
18 days until next milestone

First Submitted

Initial submission to the registry

April 29, 2023

Completed
10 days until next milestone

First Posted

Study publicly available on registry

May 9, 2023

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2023

Completed
Last Updated

May 9, 2023

Status Verified

April 1, 2023

Enrollment Period

3 months

First QC Date

April 29, 2023

Last Update Submit

April 29, 2023

Conditions

Keywords

anxietyapppsychotherapymindfulnessacceptance and commitment therapycognitive behavioural therapyrandomised controlled trialdepression

Outcome Measures

Primary Outcomes (1)

  • change in anxiety score

    sum of three slider questions on emotional state (3-sliders-score)

    immediately before and immediately after the intervention

Study Arms (14)

mindful breathing

EXPERIMENTAL
Other: intervention with this name in MindEase app

deep breathing

EXPERIMENTAL
Other: intervention with this name in MindEase app

cognitive therapy

EXPERIMENTAL
Other: intervention with this name in MindEase app

dare response

EXPERIMENTAL
Other: intervention with this name in MindEase app

defusion

EXPERIMENTAL
Other: intervention with this name in MindEase app

in flow with fear

EXPERIMENTAL
Other: intervention with this name in MindEase app

gratitude practice

EXPERIMENTAL
Other: intervention with this name in MindEase app

guided mindfulness

EXPERIMENTAL
Other: intervention with this name in MindEase app

muscle relaxation

EXPERIMENTAL
Other: intervention with this name in MindEase app

reframe your fears

EXPERIMENTAL
Other: intervention with this name in MindEase app

calming visualization

EXPERIMENTAL
Other: intervention with this name in MindEase app

reflective writing

EXPERIMENTAL
Other: intervention with this name in MindEase app

reading about anxiety

PLACEBO COMPARATOR
Other: reading about anxiety

do what you would usually do

NO INTERVENTION

Interventions

MindEase is an app which provides interventions against anxiety. The interventions are based on mindfulness, acceptance and commitment therapy, and cognitive behavioural therapy.

calming visualizationcognitive therapydare responsedeep breathingdefusiongratitude practiceguided mindfulnessin flow with fearmindful breathingmuscle relaxationreflective writingreframe your fears

Participants are given an educational text to read about anxiety.

reading about anxiety

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • anxiety score is above cut-off

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Oxford

Oxford, Oxfordshire, OX1 3QG, United Kingdom

RECRUITING

Related Publications (1)

  • Sandkuhler JF, Kahl F, Sadurska MZ, Brietbart P, Greenberg S, Brauner J. The Immediate Impact of App-Based Psychotherapeutic Exercises on Anxiety: An RCT. Depress Anxiety. 2025 Apr 2;2025:5586831. doi: 10.1155/da/5586831. eCollection 2025.

MeSH Terms

Conditions

Anxiety DisordersAlzheimer DiseaseDepression

Interventions

Methods

Condition Hierarchy (Ancestors)

Mental DisordersDementiaBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesTauopathiesNeurodegenerative DiseasesNeurocognitive DisordersBehavioral SymptomsBehavior

Intervention Hierarchy (Ancestors)

Investigative Techniques

Study Officials

  • Jan M Brauner, MD

    University of Oxford

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
QUADRUPLE
Who Masked
PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Masking Details
Participants are not told whether they are in an intervention or control condition. The app is both the care provider and the outcomes assessor. The investigator will be blinded while analysing the data.
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: Participants will be randomly assigned to an intervention or control condition.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
medical doctor

Study Record Dates

First Submitted

April 29, 2023

First Posted

May 9, 2023

Study Start

April 11, 2023

Primary Completion

July 1, 2023

Study Completion

July 1, 2023

Last Updated

May 9, 2023

Record last verified: 2023-04

Data Sharing

IPD Sharing
Will share

Anonymous participant data will be accessible to anyone upon request.

Shared Documents
STUDY PROTOCOL, SAP, CSR, ANALYTIC CODE
Time Frame
Immediately after publication. No end date.
Access Criteria
Anyone who wishes to access the data.

Locations