NCT05844176

Brief Summary

The goal of this study is to evaluate the characteristic of intracranial arterial stenosis among young patients.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
500

participants targeted

Target at P75+ for all trials

Timeline
53mo left

Started Jun 2022

Longer than P75 for all trials

Geographic Reach
1 country

4 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress47%
Jun 2022Oct 2030

Study Start

First participant enrolled

June 1, 2022

Completed
11 months until next milestone

First Submitted

Initial submission to the registry

April 25, 2023

Completed
11 days until next milestone

First Posted

Study publicly available on registry

May 6, 2023

Completed
2.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2025

Completed
5 years until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2030

Expected
Last Updated

April 24, 2025

Status Verified

April 1, 2025

Enrollment Period

3.3 years

First QC Date

April 25, 2023

Last Update Submit

April 21, 2025

Conditions

Intracranial Arterial Stenosis

Outcome Measures

Primary Outcomes (1)

  • Ischemic stroke in territory of qualifying artery

    1 year

Secondary Outcomes (4)

  • Ischemic stroke in other territory

    1 year

  • Any stroke

    1 year

  • Death

    1 year

  • Stenosis of the intracranial artery

    1 year

Other Outcomes (10)

  • Ischemic stroke in the territory of qualifying artery

    3 year

  • Ischemic stroke in other territory

    3 year

  • Any stroke

    3 year

  • +7 more other outcomes

Study Arms (2)

Symptomatic intracranial arterial stenosis

Other: Routine clinical treatment

Asymptomatic intracranial arterial stenosis

Other: Routine clinical treatment

Interventions

Routine clinical treatmentOTHER

Routine clinical treatment is based on the latest international and local guidelines

Asymptomatic intracranial arterial stenosisSymptomatic intracranial arterial stenosis

Eligibility Criteria

AgeUp to 45 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)
Sampling MethodNon-Probability Sample
Study Population

Patients with intracranial arterial stenosis

You may qualify if:

  • age \< 45 years.
  • stenosis of a major intracranial artery.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (4)

Suzhou Municipal Hoapital

Suzhou, Anhui, China

RECRUITING

The Second Hospital of Hebei Medical University

Shijiazhuang, Hebei, China

RECRUITING

Xuanwu Hospital, Capital Medical University

Beijing, 100053, China

RECRUITING

The First Affiliated Hospital of Zhengzhou University

Zhengzhou, China

RECRUITING

Central Study Contacts

Xunming Ji, MD

CONTACT

010-83199439jixm@ccmu.edu.cn

Chuanjie Wu, MD

CONTACT

010-83199439wuchuanjie@xwhosp.org

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
3 Years
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

April 25, 2023

First Posted

May 6, 2023

Study Start

June 1, 2022

Primary Completion

October 1, 2025

Study Completion (Estimated)

October 1, 2030

Last Updated

April 24, 2025

Record last verified: 2025-04

Locations

CN(4)