Association Between Carotid Plaque Length and Cardiovascular Outcomes
1 other identifier
observational
3,000
1 country
5
Brief Summary
This multicenter study involved 5 hospitals (Changhai Hospital; Yueyang Hospital of Shanghai University of Traditional Chinese Medicine; Gongli Hospital; Putuo Hospital of Shanghai University of Traditional Chinese Medicine; No. 904 Hospital of the PLA Joint Logistics Support Force Wuxi). The study enrolled 5000 consecutive patients without known CAD who underwent first coronary angiography for stable chest pain and carotid ultrasound was performed during hospitalization from January 2017 through December 2018.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jan 2017
Longer than P75 for all trials
5 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 31, 2022
CompletedFirst Submitted
Initial submission to the registry
April 25, 2023
CompletedFirst Posted
Study publicly available on registry
May 6, 2023
CompletedStudy Completion
Last participant's last visit for all outcomes
December 31, 2030
ExpectedMay 6, 2023
June 1, 2022
5.2 years
April 25, 2023
April 25, 2023
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
major adverse cardiovascular events
cardiovascular death, myocardial infarction, ischemic stroke and coronary revascularization
3 years
Secondary Outcomes (6)
all-cause death
3 years
cardiovascular death
3 years
myocardial infarction
3 years
ischemic stroke
3 years
coronary artery revascularization
3 years
- +1 more secondary outcomes
Study Arms (1)
Carotid plaque length
Patients underwent carotid ultrasonography and first coronary angiography simultaneously
Eligibility Criteria
Consecutive patients without known CAD who underwent first coronary angiography for stable chest pain and carotid ultrasound was performed during hospitalization.
You may qualify if:
- Patients who underwent coronary angiography for stable chest pain and carotid ultrasound simultaneously;
- Patients with obstructive CAD (≥50% coronary stenosis);
You may not qualify if:
- \<18 years of age;
- previous carotid surgery or significant carotid artery disease;
- prior stroke or transient ischemic attack;
- previously documented CAD (including history of myocardial infarction, acute coronary syndrome, or coronary revascularization);
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (5)
No. 904 Hospital of the PLA Joint Logistics Support Force
Wuxi, Jiangsu, 214000, China
Changhai Hospital
Shanghai, Shanghai Municipality, 200000, China
Gongli Hospital
Shanghai, Shanghai Municipality, 200000, China
Putuo Hospital
Shanghai, Shanghai Municipality, 200000, China
Yueyang Hospital
Shanghai, Shanghai Municipality, 200000, China
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Pan Li, PhD
Changhai Hospital
- STUDY DIRECTOR
Jian Jian Na, MD
Putuo Hospital
- STUDY DIRECTOR
Liang Chen, MD
904th Hospital of the Joint Logistics Support Force of the PLA
- STUDY DIRECTOR
Wei Zhang, MD
Gongli Hospital
- STUDY DIRECTOR
Yawei Yang, MD
Yueyang Hospital
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
April 25, 2023
First Posted
May 6, 2023
Study Start
January 1, 2017
Primary Completion
March 31, 2022
Study Completion (Estimated)
December 31, 2030
Last Updated
May 6, 2023
Record last verified: 2022-06