Evaluation of Antimicrobial Efficacy of Green Tea, Garlic With Lime, Pomegranate Extract and Chlorhexidine Mouth Rinses in a Group of Egyptian Children (In-Vivo Study)

NCT05841589 | Completed

• 1 other identifier: PED18-8M
• Study Type: interventional
• Target: 84
• Locations: 1 country
• Sites: 1

Brief Summary

the aim of the clinical trial is to evaluate the antimicrobial efficacy of the herbal mouth rinses against chlorhexidine mouth rinse.

Conditions

Dental Caries

Keywords

herbal mouth rinses; Pomegranate; Caries prevention; Garlic extract; Green tea extract

Outcome Measures

Primary Outcomes (1)

• patient satisfaction

  Child satisfaction was measured using a 5-point pictorial likert scale .This Facial image scale was suitable and easy way to evaluate patient satisfaction about taste, smell and willing to use the mouth rinse. Its format was graded from 1 to 5 while 1 is the most satisfied and 5 is the least satisfied

  Through study completion, an average of 1 month

Secondary Outcomes (1)

• bacterial count

  1 day after rinsing

Study Arms (4)

Green tea extract mouth rinse

EXPERIMENTAL

group green tea extract

Procedure: Green tea extract mouth rinse

Garlic with lime extract mouth rinse

EXPERIMENTAL

garlic with lime extract

Procedure: Garlic with lime extract mouth rinse

Pomegranate extract mouth rinse

EXPERIMENTAL

pomegranate extract

Procedure: Pomegranate extract mouth rinse

Chlorhexidine mouth rinse

EXPERIMENTAL

chlorhexidine

Procedure: Chlorhexidine mouth rinse

Interventions

Green tea extract mouth rinse PROCEDURE

herbal extracts mouth rinse that was prepared in the microbiology laboratory

Green tea extract mouth rinse

Garlic with lime extract mouth rinse PROCEDURE

herbal extracts mouth rinse that was prepared in the microbiology laboratory

Garlic with lime extract mouth rinse

Pomegranate extract mouth rinse PROCEDURE

herbal extracts mouth rinse that was prepared in the microbiology laboratory

Pomegranate extract mouth rinse

Chlorhexidine mouth rinse PROCEDURE

herbal extracts mouth rinse that was prepared in the microbiology laboratory

Chlorhexidine mouth rinse

Eligibility Criteria

• Age: 5 Years - 8 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17)

You may qualify if:

• No history of systemic disease.
• Patients didn't received antibiotics for at least 3 months before and during the study

You may not qualify if:

• Fixed or removable orthodontic appliances.
• Children with intra oral abscess, oral lesions or gingival diseases.
• Parental consent was not acquired

Sponsors & Collaborators

• omnia sayed: lead

Study Sites (1)

Ain Shmas University

Cairo, Egypt

Location

MeSH Terms

Conditions

Dental Caries

Condition Hierarchy (Ancestors)

Tooth Demineralization; Tooth Diseases; Stomatognathic Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Masking Details: the participant didn't know what he rinsed with the prescribed group of mouth rinse. the outcome assessor didn't know what group of mouth rinse belong to the bacterial count that was evaluated.
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Principal investigator and demonstrator at Pediatric Dentistry & Dental Public Health Department

Model Details: the four groups of the mouth rinses were done in parallel with each other

Study Record Dates

• First Submitted: March 27, 2023
• First Posted: May 3, 2023
• Study Start: February 21, 2018
• Primary Completion: November 30, 2021
• Study Completion: December 1, 2021
• Last Updated: May 3, 2023

Record last verified: 2023-04

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)