The South Texas Aging Registry and Repository
STARR
1 other identifier
observational
149
1 country
1
Brief Summary
This research registry and repository was designed because the investigators want to learn about how to improve the health and quality of life of older adults.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Feb 2019
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
February 11, 2019
CompletedFirst Submitted
Initial submission to the registry
April 18, 2023
CompletedFirst Posted
Study publicly available on registry
April 28, 2023
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 6, 2023
CompletedStudy Completion
Last participant's last visit for all outcomes
December 6, 2023
CompletedMay 7, 2024
May 1, 2024
4.8 years
April 18, 2023
May 6, 2024
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Collection of STARR repository data
De-identified repository data and samples will be made available to outside investigators for future studies related to aging
Baseline to one day
Secondary Outcomes (1)
KAPP Sen TMC repository data
Baseline to one year
Study Arms (2)
Primary Study
Community dwelling adults from the South Texas area who are interested in volunteering for research studies on aging. This will facilitate the inclusion of older adults and minority in research studies and help to increase the quantity and quality of research relating to them.
KAPP Sen Tissue Mapping Study
The substudy KAPP Sen TMC will enroll eligible STARR participants to undergo repeat assessments over two years. KAPP Sen TMC is a collaborative effort between UT Health San Antonio, Jackson Laboratory for Genomic Medicine (JAX-GM), Brigham and Women's Hospital, Joslin Diabetes Center, UConn Health Center on Aging and Mayo Clinic to characterize cellular senescence in terms of its presence and heterogeneity in healthy human tissues, as well as its tissue burden, spatial distribution, and biological features in a diverse study population.
Eligibility Criteria
Community dwelling adults from the South Texas area who are interested in volunteering for research studies on aging.
You may qualify if:
- Age 18 years or older
- Age 20 years and older
You may not qualify if:
- Inability to provide informed consent
- Pregnancy
- Diabetes
- Hypertension with end-organ damage
- BMI\>30
- GFR\<60 ml/min/1.73 m2
- Cardiovascular disease
- Pancreatitis
- Malignancy other than non-melanoma skin cancers
- Active, uncontrolled pulmonary, hepatic, infectious, gastrointestinal, endocrine, neurologic, or inflammatory disease.
- Chronic use of systemic steroids or use of agents with senolytic activity
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
The University of Texas Health Science Center at San Antonio
San Antonio, Texas, 78229, United States
Biospecimen
Blood and serum will be stored for future research after obtaining blood sugar level, and other measures such as lipids, liver and kidney function. Genetic material will be obtained from blood to provide the biology of aging and aging-related disorders. Fat samples collected from a biopsy for future genetic research. Skin tissue will be collected by a punch biopsy for future genetic research.
Study Officials
- PRINCIPAL INVESTIGATOR
Sara Espinoza, MD
University of Texas Health Science Center San Antonio
Study Design
- Study Type
- observational
- Observational Model
- OTHER
- Time Perspective
- PROSPECTIVE
- Target Duration
- 1 Year
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
April 18, 2023
First Posted
April 28, 2023
Study Start
February 11, 2019
Primary Completion
December 6, 2023
Study Completion
December 6, 2023
Last Updated
May 7, 2024
Record last verified: 2024-05
Data Sharing
- IPD Sharing
- Will share
- Shared Documents
- STUDY PROTOCOL, SAP
- Time Frame
- Requests from investigators to obtain data/specimens from the repository must be submitted in writing using an official repository request form, along with study protocol and documentation of appropriate approvals. Requests will be reviewed on a monthly basis by members of the Repository Executive Committee. Request to access data or specimens will be processed and entered into the Repository Log by the Repository Coordinator and submitted for review by the Executive Committee each month.
New prospective studies and those involving interacting with human subjects: Participants/research volunteers who agree to be re-contacted will be matched with future studies which they are likely to qualify for based upon information provided by each STARR participant at the time of enrollment and which is gathered using provided samples. KAPP Sen TMC will support the use of a web-based platform to connect and facilitate entering, sharing, and exchanging data among collaborates. Data will be exported to a web portal developed in conjunction with the CODCC where the research community can request access to molecular data and corresponding biospecimen data, such as clinical, demographic, and biospecimen handling data.