Influence of Nutritional Indices on the Prognosis of Patients With SARS-CoV-2 Infection

NCT05835102 | Recruiting

• 1 other identifier: 2023-19
• Study Type: observational
• Target: 800
• Locations: 1 country
• Sites: 1

Brief Summary

With the decline of virulence after the mutation of the SARS-CoV-2 , based on the national life and health and national development needs, the domestic SARS-CoV-2 infection epidemic prevention policy has changed, and the number of people infected by the SARS-CoV-2 has increased. Nutritional status is an indicator of human health and plays an important role in fighting disease. Malnutrition has been found to correlate with prognosis in patients infected with the SARS-CoV-2 infection . Timely identification and assessment of the patient's nutritional status and early implementation of relevant nutritional intervention are conducive to the recovery of the patient's condition. In clinical practice, it is necessary to improve nutrition as an aspect of the comprehensive diagnosis and treatment of patients with SARS-CoV-2 infection, but there is still a lack of relevant nutritional indicators or models to simply and accurately assess the nutritional status of patients.The purpose of this study was to evaluate the effects of PNI, NRI, GNRI, albumin level, vitamin D, chest muscle area and density on the clinical characteristics and prognosis of patients with SARS-CoV-2 infection, to find the nutritional predictors of severe disease in patients with SARS-CoV-2 infection, and to establish a simpler and more accurate nutritional evaluation model. To provide evidence for targeted nutritional interventions in patients with SARS-CoV-2 infection.

Conditions

COVID-19

Keywords

prognostic nutritional index; geriatric nutritional risk index; pectoralis muscle index; prognosis

Outcome Measures

Primary Outcomes (2)

• Death

  Death due to Respiratory failure or other diseases

  October 2022 to January 2023

• cure

  the patients with SARS-CoV-2 infection are cured and discharged from hospital

  October 2022 to January 2023

Study Arms (1)

Patients With SARS-CoV-2 Infection

Patients who test positive for SARS-CoV-2 nucleic acid or SARS-CoV-2 antigen

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients with a positive SARS-CoV-2 nucleic acid test or a positive SARS-CoV-2 antigen test.

You may qualify if:

• Patients with a positive SARS-CoV-2 nucleic acid test or a positive SARS-CoV-2 antigen test.

You may not qualify if:

• People with end-stage malignant tumors;
• Nutritional intake disorders, mainly dependent on enteral and parenteral nutrition supporters;
• paralyzed;
• Intravenous drug addicts.

Sponsors & Collaborators

• Juan Kang: lead

Study Sites (1)

The Second Affiliated Hospital of Chongqing Medical University

Chongqing, Chongqing Municipality, 400000, China

RECRUITING

MeSH Terms

Conditions

COVID-19

Condition Hierarchy (Ancestors)

Pneumonia, Viral; Pneumonia; Respiratory Tract Infections; Infections; Virus Diseases; Coronavirus Infections; Coronaviridae Infections; Nidovirales Infections; RNA Virus Infections; Lung Diseases; Respiratory Tract Diseases

Study Officials

• Juan Kang, M.D.

  The Second Affiliated Hospital of Chongqing Medical University

  STUDY CHAIR

Central Study Contacts

Juan Kang, M.D.

CONTACT

8613996112052; 68368892@qq.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: associate professor

Study Record Dates

• First Submitted: April 23, 2023
• First Posted: April 28, 2023
• Study Start: May 1, 2023
• Primary Completion: December 7, 2025
• Study Completion: December 9, 2025
• Last Updated: June 25, 2025

Record last verified: 2025-06

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)