NCT05832840

Brief Summary

The goal of this observational and cross-sectional study is to develop and validate a survey that can be used to identify anemia, and its severity, among pre-pregnant women allowing for the timely implementation of focused public health and personalized interventions. Participants will be asked 26 survey questions about menstrual history and provide a 5 ml venous blood sample to measure hemoglobin, ferritin, and transferrin saturation levels.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
503

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Apr 2023

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 16, 2023

Completed
1 day until next milestone

Study Start

First participant enrolled

April 17, 2023

Completed
10 days until next milestone

First Posted

Study publicly available on registry

April 27, 2023

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 13, 2023

Completed
21 days until next milestone

Study Completion

Last participant's last visit for all outcomes

July 4, 2023

Completed
Last Updated

November 18, 2023

Status Verified

November 1, 2023

Enrollment Period

2 months

First QC Date

April 16, 2023

Last Update Submit

November 16, 2023

Conditions

Keywords

Anemia

Outcome Measures

Primary Outcomes (1)

  • Validation of survey instrument

    The PREPSA Scale will be administered to pre-pregnant women and a blood draw within four weeks will be used to assess anemia status and support validation of the PREPSA Scale. The minimum value on the scale is a score of zero. The maximum value on the scale is a score of forty. This is based on the number of items plus the value of the highest coded category on items with more than one category. A higher score means a worse outcome and is associated with higher levels of iron deficient anemia.

    Up to four weeks following pre-pregnancy administration of PREPSA scale

Eligibility Criteria

Age18 Years - 25 Years
Sexfemale(Gender-based eligibility)
Healthy VolunteersYes
Age GroupsAdult (18-64)
Sampling MethodNon-Probability Sample
Study Population

Currently married pre-pregnant women (n=500), ages 18-25 years, in Belagavi, Karnataka, India

You may qualify if:

  • year old women
  • Not currently pregnant and have never been pregnant
  • Currently married
  • If last menstrual period \>6 weeks ago, exclude pregnancy via pregnancy test

You may not qualify if:

  • Currently using any form of contraception other than barrier methods

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Jawaharlal Nehru Medical College

Belagavi, India

Location

MeSH Terms

Conditions

Anemia

Condition Hierarchy (Ancestors)

Hematologic DiseasesHemic and Lymphatic Diseases

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
CROSS SECTIONAL
Sponsor Type
NETWORK
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 16, 2023

First Posted

April 27, 2023

Study Start

April 17, 2023

Primary Completion

June 13, 2023

Study Completion

July 4, 2023

Last Updated

November 18, 2023

Record last verified: 2023-11

Data Sharing

IPD Sharing
Will share

Deidentified participant data will be made available through the NICHD Data and Specimen Hub (N-DASH system, a publicly accessible online archive, following publication of the primary paper.

Shared Documents
STUDY PROTOCOL, SAP
Time Frame
No more than one year after publication of the primary paper. No end date.
Access Criteria
Access will follow procedures in accordance with those outlined by the NICHD Data and Specimen Hub (N-DASH).

Locations