NCT07135635

Brief Summary

can we predict neonatal outcome by the results of 3rd trimester MCA Doppler Indices In pregnant women with anemia?? --- the aim of this study is to evaluate values of MCA Doppler indices in determining fetal outcome in pregnant women with anemia.

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
100

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started May 2025

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
enrolling by invitation

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2025

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

August 5, 2025

Completed
17 days until next milestone

First Posted

Study publicly available on registry

August 22, 2025

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2026

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2026

Completed
Last Updated

August 22, 2025

Status Verified

August 1, 2025

Enrollment Period

1 year

First QC Date

August 5, 2025

Last Update Submit

August 14, 2025

Conditions

Anemia During PregnancyAnemia Complicating PregnancyAnemia

Outcome Measures

Primary Outcomes (2)

  • Third Trimester Middle Cerebral artery Doppler ( MCA -PSV).

    1 year

  • Assess correlation between MCA Doppler indices and neonatal Hemoglobin level

    1 year

Secondary Outcomes (4)

  • Assess correlation between MCA Doppler indices and neonatal weight.

    1 year

  • Assess correlation between MCA Doppler indices and NICU admission.

    1 year

  • Assess correlation between MCA Doppler indices and APGAR Score.

    1year

  • Assess correlation between MCA Doppler indices and placental weight.

    1 year

Interventions

Middle Cerebral Artery dopplerDIAGNOSTIC_TEST

All cases of pregnant women diagnosed with anemia at 3rd trimester will have baseline assessment of history, clinical examination, HB level, obstetric ultrasonography done then they will have Middle Cerebral Artery Doppler done to assess correlation between MCA Doppler indices \& neonatal outcomes. Then appropriate treatment of anemia will be taken.

Eligibility Criteria

Sexfemale
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

pregnant women with anemia in sohag university hospital

You may qualify if:

  • \- (1) Pregnant women diagnosed with anemia at 3rd trimester with hemoglobin level ≤ 11 g/dl.
  • (2) Singleton pregnancy.

You may not qualify if:

  • Multifetal pregnancy.
  • Fetal Anomalies.
  • Any other maternal systemic diseases other than anemia as DM, Preeclampsia, Autoimmune disease.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Faculty of Medicine- Sohag University

Sohag, Egypt

Location

MeSH Terms

Conditions

Anemia

Condition Hierarchy (Ancestors)

Hematologic DiseasesHemic and Lymphatic Diseases

Study Officials

  • Yasser Ahmed professor of obstetrics & gynecology sohag university, professor

    sohag faculty of medecine

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
specialist at elhelal hospital for health insurance

Study Record Dates

First Submitted

August 5, 2025

First Posted

August 22, 2025

Study Start

May 1, 2025

Primary Completion

May 1, 2026

Study Completion

May 1, 2026

Last Updated

August 22, 2025

Record last verified: 2025-08

Data Sharing

IPD Sharing
Will share

Locations

EG(1)