Comparison of Lumbar Muscle Thickness Measurements in Osteoporotic and Osteopenic Patients
1 other identifier
observational
301
1 country
1
Brief Summary
In osteoporosis, sarcopenia is a common condition. Sarcopenic measurements can be made by evaluating muscle thickness in different regions. We aim to evaluate lumbar muscle losses in patients with osteoporosis in the lumbar region and to examine whether these muscle losses are correlated with the level of osteoporosis. The patients will be divided into 3 groups as healthy, osteopenic and osteoporotic according to DEXA measurements. Demographic values, comorbidities, osteoporosis drugs used, fracture histories, L1-4, L2-4, femoral neck and total BMD and t values of the patients, psoas and multifidus muscle measurements will be made at L2-L3 level in Lumbar MR imaging. Lumbar MR muscle measurements will be made by 1 physician blind to the DEXA values of the patients.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Aug 2023
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
April 10, 2023
CompletedFirst Posted
Study publicly available on registry
April 21, 2023
CompletedStudy Start
First participant enrolled
August 15, 2023
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 15, 2024
CompletedStudy Completion
Last participant's last visit for all outcomes
August 30, 2024
CompletedNovember 4, 2024
November 1, 2024
1 year
April 10, 2023
November 1, 2024
Conditions
Outcome Measures
Primary Outcomes (1)
Lomber Muscle Measurement
Psoas and multifidus muscle measurements will be made at L2-L3 level in Lumbar MR imaging.
Day 1
Study Arms (3)
Ostoporotic Patients Group
T value of -2.5 and below in DEXA measurement
Osteopenic Patients Group
T value between -2.5 and -1 in DEXA measurement
Healthy Group
T value of -1 and above in DEXA measurement
Interventions
Muscle thickness measurements will be made on the imaging of those who have lumbar MR imaging.
Eligibility Criteria
50-90 years old osteoporotic, osteopenic and healthy people
You may qualify if:
- years old
- \. Recent MRI of the lumbar region with DEXA evaluation
You may not qualify if:
- Have had previous lumbar surgery
- Any previous lumbar injection
- Stage 3-4 Lumbar Listesis
- Presence of Lumbar Discopathy accompanied by neurological deficit
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Etfal Training and Research Hospital
Istanbul, Istanbul, 34100, Turkey (Türkiye)
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- CASE CROSSOVER
- Time Perspective
- CROSS SECTIONAL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Medical Doctor
Study Record Dates
First Submitted
April 10, 2023
First Posted
April 21, 2023
Study Start
August 15, 2023
Primary Completion
August 15, 2024
Study Completion
August 30, 2024
Last Updated
November 4, 2024
Record last verified: 2024-11
Data Sharing
- IPD Sharing
- Will not share