NCT05818930

Brief Summary

The goal of this observational study is to compare clinical utility between Remote EEG Monitoring (REMI) and conventional EEG in patients (6 and older) that are undergoing EEG recording in a hospital as part of their routine clinical care. The main question\[s\] it aims to answer are:

  • What is the concurrence of diagnosis made by epileptologist using REMI and full-EEG signals.
  • What is the proportion of participants experiencing as seizure at the time of sensor placement, compared between REMI sensor placement and full-EEG placement. Participants will wear REMI and conventional EEG electrodes at the same time.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
129

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Mar 2023

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 7, 2023

Completed
1 day until next milestone

Study Start

First participant enrolled

March 8, 2023

Completed
1 month until next milestone

First Posted

Study publicly available on registry

April 19, 2023

Completed
2.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2025

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2025

Completed
Last Updated

January 25, 2024

Status Verified

January 1, 2024

Enrollment Period

2.2 years

First QC Date

March 7, 2023

Last Update Submit

January 24, 2024

Conditions

Outcome Measures

Primary Outcomes (1)

  • Comparison of clinician's diagnostic impression between REMI and conventional electroencephalograph data.

    Concurrence of diagnosis made by epileptologist using REMI and full electroencephalograph signals. (I.e., a comparative count of seizure activity identified by an epileptologist using REMI EEG and using conventional EEG.)

    Through the length of time that a patient is actively monitored using both REMI and a full electroencephalograph (up to 24 hours).

Secondary Outcomes (1)

  • Comparison of time to identify epileptiform EEG signals between REMI and conventional electroencephalograph data.

    Time Frame: Through the time of sensor placement for both REMI sensors and a full electroencephalograph (approximately up to one hour).

Study Arms (1)

REMI vs Conventional EEG

OTHER

REMI EEG is as Diagnostically useful as conventional EEG at monitoring patients with suspected seizure events.

Diagnostic Test: REMI

Interventions

REMIDIAGNOSTIC_TEST

Diagnostic monitoring

REMI vs Conventional EEG

Eligibility Criteria

Age6 Years+
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Clinical EEG has been ordered for suspected seizures
  • Age 6 years or older

You may not qualify if:

  • Cannot undergo EEG recordings because of severe head or other injury that prevents EEG recording.
  • Transferred immediately for an operation
  • Hemodynamically unstable (SBP less than 90 mmHg) at time of EEG placement
  • Inability to place four REMI EEG sensors.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Utah

Salt Lake City, Utah, 84132, United States

Location

MeSH Terms

Conditions

Epilepsy

Condition Hierarchy (Ancestors)

Brain DiseasesCentral Nervous System DiseasesNervous System Diseases

Study Officials

  • Maija Holsti, MD, MPH

    University of Utah

    PRINCIPAL INVESTIGATOR
  • Amir M Arain, MD, MPH

    University of Utah

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 7, 2023

First Posted

April 19, 2023

Study Start

March 8, 2023

Primary Completion

June 1, 2025

Study Completion

October 1, 2025

Last Updated

January 25, 2024

Record last verified: 2024-01

Data Sharing

IPD Sharing
Will share

Epitel will make this highly-valuable data set available to the wider academic community. This could be done by posting appropriate data on the Epilepsy Ecosystem website: https://www.epilepsyecosystem.org/ All data collection is performed using the same Epilog Data Dictionary across clinical sites. Each PI and Study Coordinator is trained on the data dictionary reporting. This dictionary follows the Common Data Elements for Epilepsy Mobile Health Systems for which Epitel was a contributing member. The common data elements are meant to standardize to the extent possible all data collection, reporting, and analysis in the epilepsy mobile health space.

Shared Documents
STUDY PROTOCOL
Time Frame
Requests for data can be submitted starting12 months following study publication and the data may be accessible for up to 24 months.
Access Criteria
Access to trial IPD can be requested by qualified researchers, and will be provided following review and approval of a research proposal and execution of a Data Sharing Agreement.
More information

Locations