NCT05799404

Brief Summary

The aim of this study is to compare the thickness of the stapes footplate measured with ultra high resolution CT in control patients, otosclerosis patients and chronic otitis media patients.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
100

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Apr 2023

Shorter than P25 for all trials

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

December 5, 2022

Completed
4 months until next milestone

First Posted

Study publicly available on registry

April 5, 2023

Completed
23 days until next milestone

Study Start

First participant enrolled

April 28, 2023

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 28, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 28, 2023

Completed
Last Updated

April 5, 2023

Status Verified

April 1, 2023

Enrollment Period

2 months

First QC Date

December 5, 2022

Last Update Submit

April 3, 2023

Conditions

Keywords

ultra high resolutionctstapesfootplateotosclerosisotitis media

Outcome Measures

Primary Outcomes (1)

  • stapes footplate thickness in mm in the stapes axial plane

    stapes footplate thickness measured with a digital caliper on our PACS system with the accuracy of a tenth of a millimetre, under the anterior crus of the stapes, under the posterior crus of the stapes, and at its midpoint, in the stapes axial plane and in the lateral semi circular canal plane, to compare both values and find out wich one is the most pertinent

    october 2020-october 2022

Secondary Outcomes (1)

  • interobserver variability

    october 2020-october 2022

Study Arms (3)

otosclerosis

otosclerosis patients

Diagnostic Test: ultra-high resolution CT

chronic otitis media

otitis media with middle ear opacities

Diagnostic Test: ultra-high resolution CT

controls

sudden ear loss, pre-implantatory imaging, vertigo, tympanic perforation

Diagnostic Test: ultra-high resolution CT

Interventions

stapes footplate thickness measurement

chronic otitis mediacontrolsotosclerosis

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

patients refered to our department between october 2020 and October 2022 for an ultra high resolution CT of the temporal bone

You may qualify if:

  • Ultra high resolution CT of the temporal bone available

You may not qualify if:

  • previous surgery

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (2)

  • Akazawa Y, Ganaha A, Higa T, Kondo S, Oyakawa Y, Hirakawa H, Suzuki M, Yamashiro T. Measurement of stapes footplate thickness in otosclerosis by ultra-high-resolution computed tomography. Acta Otolaryngol. 2020 Nov;140(11):899-903. doi: 10.1080/00016489.2020.1788225. Epub 2020 Jul 23.

    PMID: 32700991BACKGROUND
  • Tang R, Yin H, Wang Z, Zhang Z, Zhao L, Zhang P, Li J, Zhao P, Lv H, Zhang L, Yang Z, Wang Z. Stapes visualization by ultra-high resolution CT in cadaveric heads: A preliminary study. Eur J Radiol. 2021 Aug;141:109786. doi: 10.1016/j.ejrad.2021.109786. Epub 2021 May 21.

    PMID: 34058698BACKGROUND

MeSH Terms

Conditions

OtosclerosisOtitis Media

Condition Hierarchy (Ancestors)

Ear DiseasesOtorhinolaryngologic DiseasesOtitis

Study Officials

  • romain gillet, MD

    CHRU de Nancy

    PRINCIPAL INVESTIGATOR

Central Study Contacts

romain gillet, MD

CONTACT

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
MD, MSK Radiologist

Study Record Dates

First Submitted

December 5, 2022

First Posted

April 5, 2023

Study Start

April 28, 2023

Primary Completion

June 28, 2023

Study Completion

June 28, 2023

Last Updated

April 5, 2023

Record last verified: 2023-04

Data Sharing

IPD Sharing
Will not share