Analysis of Heart Rate Variability After a Physical Exercise Session

NCT05798975 | Completed

• 1 other identifier: 5964/21
• Study Type: interventional
• Target: 36
• Locations: 1 country
• Sites: 1

Brief Summary

Systemic arterial hypertension (SAH) is a multifactorial clinical condition, characterized by sustained elevation of blood pressure levels, contributing to 50% of deaths from cardiovascular disease. The Autonomic Nervous System (ANS) plays a fundamental role in the regulation of Blood Pressure (BP) and is closely associated with Heart Rate (HR). HR changes are called Heart Rate Variability (HRV). In individuals with SAH, HRV indices are reduced compared to normotensive individuals, showing changes in autonomic modulation, thus increasing the risk for cardiovascular events. The objective of this study will be to analyze the Heart Rate Variability in individuals with controlled SAH after a session of aerobic (EA) or resistance (RE) physical exercise.

Conditions

Hypertension

Outcome Measures

Primary Outcomes (1)

• Heart Rate Variability.

  Analysis of heart rate variability with Wincardio Digital ECG.

  4 hours

Study Arms (3)

Aerobic Physical Exercise

EXPERIMENTAL

Cycle ergometer exercise

Other: Resistance Exercise. 1 session of acute exercise; Other: no exercise

Resistance Physical Exercise

EXPERIMENTAL

Exercise with weights

Other: Aerobic Exercise. 1 session of acute exercise; Other: no exercise

Control

NO INTERVENTION

No exercise. Rest

Interventions

Aerobic Exercise. 1 session of acute exercise OTHER

40 minutes on cycle ergometer, 60% of heart rate reserve

Resistance Physical Exercise

Resistance Exercise. 1 session of acute exercise OTHER

2 exercises for lower limbs and 2 for upper limbs with 4 sets of 12 repetitions at 60% 1-RM. 40 minutes

Aerobic Physical Exercise

no exercise OTHER

Rest

Aerobic Physical Exercise; Resistance Physical Exercise

Eligibility Criteria

• Age: 30 Years - 59 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Controlled Systemic Alterial Hypertension

You may not qualify if:

• Diabetes mellitus;
• heart failure;
• coronary artery disease;
• chronic renal failure;
• body mass index (BMI) ≥ 35 kg/m2;
• smokers;
• individuals with injuries to the upper and lower limbs that make the exercise protocol impossible;
• not using antihypertensive medication and using beta-blocker and/or alpha-blocker medication.

Sponsors & Collaborators

• Instituto de Cardiologia do Rio Grande do Sul: lead

Study Sites (1)

Diego Silveira da Silva

Porto Alegre, Rio Grande do Sul, Brazil

Location

MeSH Terms

Conditions

Hypertension

Condition Hierarchy (Ancestors)

Vascular Diseases; Cardiovascular Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, CARE PROVIDER
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: physical education professor.

Model Details: AE= Aerobic Exercise RE= Resistance Exercise CT= Control (no exercise)

Study Record Dates

• First Submitted: February 10, 2023
• First Posted: April 5, 2023
• Study Start: April 1, 2022
• Primary Completion: October 1, 2024
• Study Completion: November 30, 2024
• Last Updated: May 14, 2025

Record last verified: 2025-05

Data Sharing

• IPD Sharing: Will not share

Locations

BR (1)