NCT05780788

Brief Summary

Characterizing orthodontic tooth movements in real time by using photographic scans to monitor teeth movement. The photographic scans will also be compared to 3D model scans. Canine retraction over the course of 1 orthodontic visit will be measured.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
36

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Dec 2020

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 31, 2020

Completed
2.2 years until next milestone

First Submitted

Initial submission to the registry

February 28, 2023

Completed
23 days until next milestone

First Posted

Study publicly available on registry

March 23, 2023

Completed
12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 20, 2024

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 30, 2024

Completed
1.5 years until next milestone

Results Posted

Study results publicly available

December 17, 2025

Completed
Last Updated

December 17, 2025

Status Verified

December 1, 2025

Enrollment Period

3.2 years

First QC Date

February 28, 2023

Results QC Date

June 26, 2025

Last Update Submit

December 1, 2025

Conditions

Canine Retraction

Outcome Measures

Primary Outcomes (1)

  • Accuracy Between Patient-taken DM Scan and Provider-taken iTero Scan

    Deviation between the photographic and intraoral scan will be measured via root mean square (RMS) in millimeters (mm).

    Initial Deviation T0 (Baseline), Final Deviation T9 (34-37 days)

Secondary Outcomes (4)

  • Tracking Maxillary Canine Tooth Movement (Displacement)

    T1 (3-5 days), T2 (6-9 days), T3 (10-13 days), T4 (14-17 days), T5 (18-21 days), T6 (22-25 days), T7 (26-29 days), T8 (30-33 days), T9 (34-37days).

  • Tracking Maxillary First Molar Movement (Displacement)

    T1 (3-5 days), T2 (6-9 days), T3 (10-13 days), T4 (14-17 days), T5 (18-21 days), T6 (22-25 days), T7 (26-29 days), T8 (30-33 days), T9 (34-37days).

  • Tracking Maxillary Canine Tooth Movement (Rotation)

    T1 (3-5 days), T2 (6-9 days), T3 (10-13 days), T4 (14-17 days), T5 (18-21 days), T6 (22-25 days), T7 (26-29 days), T8 (30-33 days), T9 (34-37days).

  • Tracking Maxillary First Molar Displacement (Rotation)

    T1 (3-5 days), T2 (6-9 days), T3 (10-13 days), T4 (14-17 days), T5 (18-21 days), T6 (22-25 days), T7 (26-29 days), T8 (30-33 days), T9 (34-37days).

Study Arms (1)

Canine retraction arm

EXPERIMENTAL

Canine retraction

Device: Monitoring Tooth Movement

Interventions

Monitoring Tooth MovementDEVICE

Monitoring Canine Retraction

Canine retraction arm

Eligibility Criteria

Age11 Years+
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Patients with fixed orthodontic appliances
  • Treatment plan requiring extraction of at least one maxillary premolar
  • Male and female
  • Permanent dentition from first molar to first molar in the maxilla
  • Teeth with normal crown morphology
  • Fully erupted canines
  • Above 11 years of age
  • Patients with any cellular phone with a camera

You may not qualify if:

  • Lack of extraction in orthodontic treatment plan
  • Syndromic patients
  • Cleft lip/palate patients
  • Removable appliances

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

UConn Health

Farmington, Connecticut, 06030, United States

Location

Results Point of Contact

Title
Dr. Flavio Uribe (Study principal investigator)
Organization
UConn Health - Department of Orthodontics
furibe@uchc.edu
8606792550

Study Officials

  • Flavio Uribe, DDS

    UConn Health

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

February 28, 2023

First Posted

March 23, 2023

Study Start

December 31, 2020

Primary Completion

March 20, 2024

Study Completion

June 30, 2024

Last Updated

December 17, 2025

Results First Posted

December 17, 2025

Record last verified: 2025-12

Data Sharing

IPD Sharing
Will not share

Locations

US(1)