NCT05776420

Brief Summary

This randomized controlled trial (RCT) will determine if access to a voucher for healthy foods reduces blood sugar levels among people living on a low income who have type 2 diabetes or elevated blood sugar.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
390

participants targeted

Target at P50-P75 for phase_3

Timeline
10mo left

Started Mar 2023

Typical duration for phase_3

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress80%
Mar 2023Apr 2027

First Submitted

Initial submission to the registry

February 3, 2023

Completed
2 months until next milestone

First Posted

Study publicly available on registry

March 20, 2023

Completed
1 day until next milestone

Study Start

First participant enrolled

March 21, 2023

Completed
4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2027

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2027

Last Updated

February 10, 2026

Status Verified

February 1, 2025

Enrollment Period

4 years

First QC Date

February 3, 2023

Last Update Submit

February 5, 2026

Conditions

Outcome Measures

Primary Outcomes (1)

  • Hemoglobin A1c

    Change in hemoglobin A1c

    6 months

Secondary Outcomes (6)

  • General health ("In general, how would you rate your health today?")

    6 months

  • Financial security ("Do you have trouble making ends meet at the end of the month?")

    6 months

  • Food insecurity measured by 6 questions from Household Food Security Survey

    6 months

  • Fruit and vegetable consumption

    6 months

  • Health care utilization using administrative data

    6 months

  • +1 more secondary outcomes

Study Arms (4)

Food voucher

EXPERIMENTAL

$65 monthly voucher for healthy foods (phase 1)

Behavioral: Food voucher

Control

NO INTERVENTION

Large voucher

EXPERIMENTAL

$160 monthly voucher for healthy foods (phase 2)

Behavioral: Food voucher

Small voucher

ACTIVE COMPARATOR

$40 monthly voucher for healthy foods (phase 2)

Behavioral: Food voucher

Interventions

Food voucherBEHAVIORAL

A voucher of that can be redeemed for food at grocery stores.

Food voucherLarge voucherSmall voucher

Eligibility Criteria

Age19 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • hemoglobin A1c 6.0 to 11.0
  • report food insecurity or financial insecurity

You may not qualify if:

  • live with a current study participant
  • life expectancy \< 6 months
  • multiple life-threatening allergies to common foods
  • require total parenteral nutrion
  • blood dyscrasia that interferes with hemoglobin A1c interpretation
  • hemoglobin A1c \>11

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

St Michael's Hospital Academic Family Health Team

Toronto, Canada

RECRUITING

Related Publications (1)

  • Persaud N, Ul Haq MZ, Buadu A, Sabir A, Sinha L, Thorpe KE, Xu K, Hwang SW, Pinto AD, Gucciardi E. Voucher for Healthy Foods and Diabetes Control: A Randomized Clinical Trial. JAMA Intern Med. 2025 Dec 1;185(12):1434-1441. doi: 10.1001/jamainternmed.2025.5420.

MeSH Terms

Conditions

Diabetes Mellitus, Type 2

Condition Hierarchy (Ancestors)

Diabetes MellitusGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System Diseases

Central Study Contacts

Study Design

Study Type
interventional
Phase
phase 3
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 3, 2023

First Posted

March 20, 2023

Study Start

March 21, 2023

Primary Completion (Estimated)

April 1, 2027

Study Completion (Estimated)

April 1, 2027

Last Updated

February 10, 2026

Record last verified: 2025-02

Data Sharing

IPD Sharing
Will share

We plan to share de-identified individual participant data

Locations