NCT05771350

Brief Summary

this study aimed to compare the removal of indoxyl sulphate between hemodiafiltration, high flux hemodialysis and low flux hemodialysis

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Nov 2016

Shorter than P25 for not_applicable

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 15, 2016

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 15, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 15, 2017

Completed
6.1 years until next milestone

First Submitted

Initial submission to the registry

March 5, 2023

Completed
11 days until next milestone

First Posted

Study publicly available on registry

March 16, 2023

Completed
Last Updated

March 16, 2023

Status Verified

March 1, 2023

Enrollment Period

2 months

First QC Date

March 5, 2023

Last Update Submit

March 5, 2023

Conditions

Hemodialysis

Outcome Measures

Primary Outcomes (1)

  • dialytic removal of indoxyl sulpahte

    assessed by the reduction ration of indoxyl sulphate

    one month when all samples were collected

Study Arms (3)

online hemodiafiltration

EXPERIMENTAL
Procedure: online hemodiafiltration

high flux hemodialysis

ACTIVE COMPARATOR
Procedure: high flux hemodialysis

low flux hemodialysis

ACTIVE COMPARATOR
Procedure: low flux hemodialysis

Interventions

online hemodiafiltrationPROCEDURE

20 patients on regular hemodialysis received online hemodiafiltration

online hemodiafiltration
high flux hemodialysisPROCEDURE

20 patients on regular hemodialysis received high flux hemodialysis

high flux hemodialysis
low flux hemodialysisPROCEDURE

20 patients on regular hemodialysis received low flux hemodialysis

low flux hemodialysis

Eligibility Criteria

Age18 Years - 75 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • maintenance hemodialysis patients aged more than 18 years

You may not qualify if:

  • active illnesses, hospitalization, malignancy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Dr

Study Record Dates

First Submitted

March 5, 2023

First Posted

March 16, 2023

Study Start

November 15, 2016

Primary Completion

January 15, 2017

Study Completion

January 15, 2017

Last Updated

March 16, 2023

Record last verified: 2023-03