NCT02261025

Brief Summary

The aim of present study is to examine the effect of low-dose aspirin on the incidence of cardiovascular events and mortality in patients undergoing chronic hemodialysis.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
410

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jan 2008

Longer than P75 for not_applicable

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2008

Completed
6.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2014

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2014

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

October 6, 2014

Completed
3 days until next milestone

First Posted

Study publicly available on registry

October 9, 2014

Completed
Last Updated

October 23, 2014

Status Verified

October 1, 2014

Enrollment Period

6.7 years

First QC Date

October 6, 2014

Last Update Submit

October 22, 2014

Conditions

Hemodialysis

Keywords

aspirin

Outcome Measures

Primary Outcomes (1)

  • survival rate

    5 years

Secondary Outcomes (1)

  • cardio-cerebral event

    5 years

Study Arms (2)

Aspirin group

EXPERIMENTAL

Aspirin 75-100mg,per day，oral

Drug: acetylsalicylic acid

non-aspirin group

NO INTERVENTION

No interventions

Interventions

acetylsalicylic acidDRUG

75-100mg,per day

Also known as: Aspirin
Aspirin group

Eligibility Criteria

Age18 Years - 85 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may not qualify if:

  • History of gastric or duodenal ulcers Known allergy to aspirin or other NSAIDs

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (1)

  • Liu J, Pan Y, Chen L, Qiao QY, Wang J, Pan LH, Gu YH, Gu HF, Fu SK, Jin HM. Low-dose aspirin for prevention of cardiovascular disease in patients on hemodialysis: A 5-y prospective cohort study. Hemodial Int. 2016 Oct;20(4):548-557. doi: 10.1111/hdi.12409. Epub 2016 Mar 1.

    PMID: 26932276DERIVED

MeSH Terms

Interventions

Aspirin

Intervention Hierarchy (Ancestors)

SalicylatesHydroxybenzoatesPhenolsBenzene DerivativesHydrocarbons, AromaticHydrocarbons, CyclicHydrocarbonsOrganic Chemicals

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Shanghai Jiao Tong University School of Medicine

Study Record Dates

First Submitted

October 6, 2014

First Posted

October 9, 2014

Study Start

January 1, 2008

Primary Completion

September 1, 2014

Study Completion

September 1, 2014

Last Updated

October 23, 2014

Record last verified: 2014-10