Trials Sponsors Conditions Drugs Pricing

Conditions

Crohn Disease Food Allergy

Outcome Measures

Primary Outcomes (2)

Bowel wall thickness
Thickness of the bowel wall measured in high-frequency ultrasound from the center of the lumen to the serosa
T0: Baseline after mild diet. T1: After provocative diet (up to 30 days from T0)
Peak Enhancement
Maximum point of the DCE-US curve assessed in Contrast-Enhanced Ultrasound
T0: Baseline after mild diet. T1: After provocative diet (up to 30 days from T0)

Study Arms (3)

Active Crohn´s disease

Ultrasound in patients with proven active Crohn´s disease scheduled for therapy with anti tumor necrosis factor alpha antibodies

Patients with Food allergy

Patients with proven food allergy

Other: Mild dietOther: Provocative diet

Healthy controls

Healthy, food-tolerant volunteers without any abdominal complaint

Other: Mild dietOther: Provocative diet

Interventions

Mild dietOther

Healthy controlsPatients with Food allergy

Provocative dietOther

Healthy controlsPatients with Food allergy

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

Eligibility Criteria

Age18 Years+

Sexall

Healthy VolunteersYes

Age GroupsAdult (18-64), Older Adult (65+)

Sampling MethodNon-Probability Sample

Study Population

Tertiary-care university hospital, patients diagnosed and treated in the outpatient department for inflammatory and allergic bowel diseases

You may qualify if:

Age over 18

Sponsors & Collaborators

Friedrich-Alexander-Universität Erlangen-Nürnberg
Otherlead

MeSH Terms

Conditions

Crohn DiseaseFood Hypersensitivity

Condition Hierarchy (Ancestors)

Inflammatory Bowel DiseasesGastroenteritisGastrointestinal DiseasesDigestive System DiseasesIntestinal DiseasesHypersensitivity, ImmediateHypersensitivityImmune System Diseases

Study Officials

Dane Wildner, M.D.
Department of Medicine 1, Divison of ultrasound medicine, University Hospital Erlangen
PRINCIPAL INVESTIGATOR

Enrollment

48 participants (actual enrollment reported by the registry).

Study Design

Study Type: observational
Observational Model: COHORT
Time Perspective: PROSPECTIVE
Sponsor Type: OTHER
Responsible Party: PRINCIPAL INVESTIGATOR
PI Title: Principal Investigator - Deputy Head of Ultrasound Department, Department of Internal Medicine 1, Universitätsklinikum Erlangen

Study Record Dates

First Submitted

February 28, 2023

First Posted

March 15, 2023

Study Start

December 6, 2012

Actual (reported)

Contrast-enhanced Ultrasound in Patients With Crohn´s Disease and Food Allergy

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Conditions

Outcome Measures

Primary Outcomes (2)

Study Arms (3)

Active Crohn´s disease

Patients with Food allergy

Healthy controls

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Conditions

Outcome Measures

Primary Outcomes (2)

Study Arms (3)

Active Crohn´s disease

Patients with Food allergy

Healthy controls

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record