European Multicenter Study on Role of Lymph Node Dissection in Surgical Management of Adrenal Cortical Carcinoma
LACC
1 other identifier
observational
90
1 country
1
Brief Summary
This project will evaluate of the number of patients who underwent adrenalectomy for ACC in different European centers using the EUROCRINE® database. The analysis will focus on the extent of lymph nodal dissection (i.e. number of lymph nodes and nodal stations dissected during adrenalectomy). We aim to evaluate the oncologic radicality of surgical treatment and the rate of tumour recurrences after surgery and nodal metastasis related to the stage of the disease and to tumour side (left/right).
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Dec 2022
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
December 15, 2022
CompletedFirst Submitted
Initial submission to the registry
February 28, 2023
CompletedFirst Posted
Study publicly available on registry
March 10, 2023
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2023
CompletedStudy Completion
Last participant's last visit for all outcomes
September 1, 2023
CompletedMarch 20, 2023
February 1, 2023
6 months
February 28, 2023
March 16, 2023
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
Incidence of Adrenocortical Carcinoma (ACC) among European endocrine centers
Identification of the number of patients who underwent adrenalectomy for diagnosis of ACC among European centers participating in the Eurocrine database
January 2015- January 2021
Extent of lymphadenectomy
Evaluation of the lymph node dissection extension (in terms of number of lymph nodes and nodal stations dissected during surgical treatment for ACC)
January 2015- January 2021
Secondary Outcomes (1)
Oncologic outcomes
January 2015- January 2021
Study Arms (1)
Adrenalectomy in patients operated for Adrenocortical Carcinoma
All adult (18 years old and older) patients registered in EUROCRINE® database that underwent surgery for adrenocortical carcinoma from 2015 till 2021 will be included
Interventions
Regarding lymphadenectomy extent, it will be described as locoregional or systematic depending on availability of data in the Eurocrine database.
Eligibility Criteria
Patients with final histology of adrenocortical carcinoma operated among European centers that participate in the Eurocrine® database between 2015 and 2021
You may qualify if:
- All adult (18 years old and older) patients
- underwent surgery
- final histology of adrenocortical carcinoma
- among European centers that participate in the Eurocrine® database between 2015 and 2021
You may not qualify if:
- Patients \<18 years old
- Patients with metastatic disease at time of clinical referral
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Rome, 00168, Italy
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Marco Raffaelli, Prof
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
February 28, 2023
First Posted
March 10, 2023
Study Start
December 15, 2022
Primary Completion
June 1, 2023
Study Completion
September 1, 2023
Last Updated
March 20, 2023
Record last verified: 2023-02