Key Insights

Highlights

Success Rate

72% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 72/100

Termination Rate

14.0%

8 terminated out of 57 trials

Success Rate

72.4%

-14.1% vs benchmark

Late-Stage Pipeline

5%

3 trials in Phase 3/4

Results Transparency

29%

6 of 21 completed with results

Key Signals

6 with results72% success

Data Visualizations

Phase Distribution

40Total
Early P 1 (2)
P 1 (12)
P 2 (23)
P 3 (3)

Trial Status

Completed21
Recruiting11
Terminated8
Unknown8
Active Not Recruiting7
Enrolling By Invitation1

Trial Success Rate

72.4%

Benchmark: 86.5%

Based on 21 completed trials

Clinical Trials (57)

Showing 20 of 20 trials
NCT03127774Phase 2Active Not RecruitingPrimary

Surgery and Heated Intraperitoneal Chemotherapy for Adrenocortical Carcinoma

NCT03050268Recruiting

Familial Investigations of Childhood Cancer Predisposition

NCT06066333Phase 2RecruitingPrimary

Study of Radiotherapy and Pembrolizumab in People With Adrenocortical Carcinoma

NCT04119024Phase 1Recruiting

Gene Modified Immune Cells After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumors

NCT04358107Active Not RecruitingPrimary

Optimal Methods of Disease Progression and Survival Analysis in Children and Adults Patients With Adrenocortical Cancer (ACC)

NCT04187404Phase 1TerminatedPrimary

A Novel Therapeutic Vaccine (EO2401) in Metastatic Adrenocortical Carcinoma, or Malignant Pheochromocytoma/Paraganglioma

NCT05036434Phase 2Active Not RecruitingPrimary

Phase II Trial of Pembrolizumab Plus Lenvatinib in Advanced Adrenal Cortical Carcinoma

NCT03333616Phase 2Active Not Recruiting

Nivolumab Combined With Ipilimumab for Patients With Advanced Rare Genitourinary Tumors

NCT03746431Phase 1Terminated

A Phase 1 Study of [225Ac]-FPI-1434 Injection

NCT02324647Completed

Structured Evaluation of adRENal Tumors Discovered Incidentally - Prospectively Investigating the Testing Yield

NCT06333314Phase 2Recruiting

Dostarlimab for Locally Advanced or Metastatic Cancer (Non-colorectal/Non-endometrial) With Tumor dMMR/MSI

NCT00453674RecruitingPrimary

German Adrenocortical Carcinoma Registry

NCT00568139Active Not RecruitingPrimary

Evaluation of Side Effects of Mitotane

NCT00669266Recruiting

Adrenal Tumors - Pathogenesis and Therapy

NCT00457587Active Not RecruitingPrimary

Preclinical Study Towards an Immunotherapy in Adrenocortical Carcinoma

NCT05634577Phase 2TerminatedPrimary

A Phase II Study to Evaluate the Efficacy and Safety of Pembrolizumab in Combination With Mitotane in Patients With Advanced Adrenocortical Carcinoma

NCT06587802Phase 2RecruitingPrimary

Phase II Study of PD-1 Antibody Combined With Radiotherapy in Recurrent or Metastatic Adrenal Cortical Carcinoma

NCT02673333Phase 2Active Not RecruitingPrimary

Single Agent Pembrolizumab in Subjects With Advanced Adrenocortical Carcinoma

NCT05563467Phase 2RecruitingPrimary

Pembrolizumab in the Treatment of Advanced, Progressive Adrenocortical Carcinoma.

NCT05999292Phase 1TerminatedPrimary

Phase 1 Study of 68Ga-R8760

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