Study of the Characteristics of Pruritus in Patients With Frontal Fibrosing Alopecia or Lichen Planus Pilaris

NCT05761158 | Terminated

• 1 other identifier: 29BRC22.0227
• Study Type: observational
• Target: 21
• Locations: 1 country
• Sites: 1

Brief Summary

The prevalence of pruritus has been studied in frontal fibrosis alopecia (FFA) and lichen planus pilaris (LPP), but there are no studies evaluating the characteristics of pruritus, the correlation between pruritus and disease activity, and its impact on quality of life. The knowledge of the characteristics of pruritus, of the link "disease activity - pruritus", and its impact on the quality of life could allow us to modify the management of the patient (modification or intensification of therapy, close monitoring...)

Conditions

Alopecia; Lichen Planus

Outcome Measures

Primary Outcomes (2)

• Study of the characteristics of pruritus in patients with frontal fibrosis alopecia or lichen planus pilaris

  Questionnaire of Brest

  Hour1

• Study of the characteristics of pruritus in patients with frontal fibrosis alopecia or lichen

  5D itch scale

  Hour1

Secondary Outcomes (3)

• Study the relationship between disease activity (AFF or LPP) and pruritus, as well as the impact of pruritus on patients' quality of life.

  Hour1

• Study the relationship between disease activity (AFF or LPP) and pruritus, as well as the impact of pruritus on patients' quality of life.

  Hour1

• Study the relationship between disease activity (AFF or LPP) and pruritus, as well as the impact of pruritus on patients' quality of life.

  Hour1

Study Arms (1)

patient

patients answer the same questionnaire whether they have frontal alopecia or lichen planus pilaris

Other: questionnaire

Interventions

questionnaire OTHER

patients are asked to complete a questionnaire

patient

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Major patients with frontal fibrosing alopecia or lichen planus pilaris, with scalp pruritus, followed in the Dermatology Department of the CHRU Brest and having given their consent to participate in the study.

You may qualify if:

• Major patient.
• Fibrosing frontal alopecia or lichen planus pilaris
• Presence of pruritus of the scalp : a positive response to the question "do you experience itchy scalp?"
• The patient received an information note and did not object to the study

You may not qualify if:

• Patients under 18 years of age.
• Other pathologies causing scalp pruritus (seborrheic dermatitis, contact dermatitis, lupus, Quinquaud's decalcifying folliculitis, ectoparasitosis, scalp psoriasis, ringworm, red sclap syndrome, dermatomyositis, central centrifugal cicatricial alopecia (CCCA))
• Refusal to participate by the patient.
• Patient under legal protection (curatorship, guardianship, ...)
• Patient not covered by social security

Sponsors & Collaborators

• University Hospital, Brest: lead

Study Sites (1)

CHU Brest

Brest, 29200, France

Location

MeSH Terms

Conditions

Alopecia; Lichen Planus

Interventions

Surveys and Questionnaires

Condition Hierarchy (Ancestors)

Hypotrichosis; Hair Diseases; Skin Diseases; Skin and Connective Tissue Diseases; Pathological Conditions, Anatomical; Pathological Conditions, Signs and Symptoms; Lichenoid Eruptions; Skin Diseases, Papulosquamous

Intervention Hierarchy (Ancestors)

Data Collection; Epidemiologic Methods; Investigative Techniques; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 1, 2023
• First Posted: March 9, 2023
• Study Start: March 14, 2023
• Primary Completion: May 25, 2023
• Study Completion: May 25, 2023
• Last Updated: April 24, 2025

Record last verified: 2025-01

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL
• Time Frame: Data will be available beginning three years and ending fifteen years following the final study report completion
• Access Criteria: Data access requests will be reviewed by the internal committee of Brest UH. Requestors will be required to sign and complete a data access agreement.

Locations

FR (1)