NCT05747300

Brief Summary

compare the clinical and radiographic success of mineral trioxide aggregate (MTA) versus premixed bioceramic paste (Wellroot PT) as pulpotomy medicaments in primary molars.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
24

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Mar 2023

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 17, 2023

Completed
11 days until next milestone

First Posted

Study publicly available on registry

February 28, 2023

Completed
1 day until next milestone

Study Start

First participant enrolled

March 1, 2023

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2024

Completed
9 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2024

Completed
Last Updated

February 28, 2023

Status Verified

February 1, 2023

Enrollment Period

1 year

First QC Date

February 17, 2023

Last Update Submit

February 17, 2023

Conditions

Keywords

Pulpotomy wellroot PT bioceramic paste

Outcome Measures

Primary Outcomes (4)

  • Post-operative pain

    Binary (present/absent) Verbal question to patient/ parent

    1 year

  • Soft tissue pathology

    Binary (present/absent) Visual clinical examination

    1 year

  • Pain to percussion

    Binary (present/absent) Percussion test by the back of the dental mirror

    1 year

  • Pathologic mobility

    Binary (present/absent) Mobility test (pressure using the end of two dental mirrors)

    1 year

Secondary Outcomes (1)

  • Absence of furcation or periapical radiolucency Absence of external or internal root resorption

    1 year

Study Arms (2)

MTA pulpotomy

ACTIVE COMPARATOR

Vital pulpotomy primary Molars using MTA

Other: Premixed bioceramic paste wellroot PT

Wellroot PT pulpotomy

EXPERIMENTAL

Vital pulpotomy primary Molars using premixed bioceramic paste wellroot PT

Other: Premixed bioceramic paste wellroot PT

Interventions

Vital pulpotomy primary Molars using premixed bioceramic paste wellrootPT

Also known as: Wellroot PT
MTA pulpotomyWellroot PT pulpotomy

Eligibility Criteria

Age4 Years - 7 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • Children aged between 4 years and 7 years.
  • Mandibular second primary molar with deep caries involving pulp.
  • No history of spontaneous pain, pathologic mobility, draining sinus tract, redness or swelling of the vestibule.
  • Normal gingival and periodontal condition, with no sensitivity to vestibular palpation, and no pain on percussion test.
  • Radiographic criteria:
  • No sign of radiolucency in periapical or furcation area.
  • No widening of PDL space or loss of lamina dura continuity.
  • No evidence of internal/external pathologic root resorption.

You may not qualify if:

  • Uncooperative children.
  • Children with systemic disease.
  • Lack of informed consent by the child patient's parent.
  • Unable to attend follow-up visits.
  • Refusal of participation.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Doaa Gamal Mohamed

Study Record Dates

First Submitted

February 17, 2023

First Posted

February 28, 2023

Study Start

March 1, 2023

Primary Completion

March 1, 2024

Study Completion

December 1, 2024

Last Updated

February 28, 2023

Record last verified: 2023-02