NCT05747118

Brief Summary

The goal of this study is to investigate to what extent a 12-week training course for people with type 2 diabetes mellitus (T2DM) or MODY can be conducted in a clinical context with clinically relevant improvements in cardiometabolic risk factors and quality of life? The main questions it aims to answer are:

  1. 1.To investigate the feasibility of supervised training for people with T2DM or MODY in a clinical context in Greenland.
  2. 2.To investigate evidence of the effect of combined aerobic and strength training on cardiometabolic risk factors and mental well-being.
  3. 3.To investigate the signs of efficacy and different interactions with the type of disease.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
18

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Aug 2022

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 15, 2022

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2022

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

February 7, 2023

Completed
21 days until next milestone

First Posted

Study publicly available on registry

February 28, 2023

Completed
Last Updated

April 12, 2023

Status Verified

April 1, 2023

Enrollment Period

5 months

First QC Date

February 7, 2023

Last Update Submit

April 10, 2023

Conditions

Outcome Measures

Primary Outcomes (1)

  • Adherence

    Adherence is in this study the proportion of completed training sessions (n=0-24 training sessions). The number of completed training sessions was registered by the physiotherapists.

    Baseline to 12 weeks

Secondary Outcomes (11)

  • Change in quality of life

    Baseline to 12 weeks

  • Change in BMI

    Baseline to 12 weeks

  • Change in fat mass

    Baseline to 12 weeks

  • Change in muscle mass

    Baseline to 12 weeks

  • Change in bone mass

    Baseline to 12 weeks

  • +6 more secondary outcomes

Study Arms (2)

Intervention

People with type 2 diabetes or MODY in the training group

Behavioral: Physical training

Control

People with type 2 diabetes or MODY in the control group

Interventions

A 12 week supervised training intervention with 1 hour physical training two times a week.

Intervention

Eligibility Criteria

Age18 Years+
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

All participants were recruited within the Capital of Greenland, Nuuk. Males and females \>18 years old and diagnosed with T2DM or MODY were included. The exclusion criteria were severe heart disease.

You may qualify if:

  • Type 2 diabetes or MODY
  • Living in the capital in Greenland, Nuuk

You may not qualify if:

  • Severe heart disease

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Steno Diabetes Center Greenland

Nuuk, 3900, Greenland

Location

MeSH Terms

Conditions

Diabetes Mellitus, Type 2

Interventions

Physical Conditioning, Human

Condition Hierarchy (Ancestors)

Diabetes MellitusGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System Diseases

Intervention Hierarchy (Ancestors)

ExerciseMotor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
MSc in Public Health, PhD student

Study Record Dates

First Submitted

February 7, 2023

First Posted

February 28, 2023

Study Start

August 15, 2022

Primary Completion

December 31, 2022

Study Completion

December 31, 2022

Last Updated

April 12, 2023

Record last verified: 2023-04

Data Sharing

IPD Sharing
Will not share

Locations