Motivation Skills Training for Schizophrenia

NCT05746455 | Completed Results

• 2 other identifiers: 8394-11R34MH129552-01A1
• Study Type: interventional
• Target: 8
• Locations: 1 country
• Sites: 1

Brief Summary

This study will take place at one outpatient clinic serving adults with serious mental illness and will recruit ten individuals (N=10) with a DSM-5 diagnosis of schizophrenia or schizoaffective disorder to participate in an Open Trial of Motivation Skills Training (MST). MST is a weekly group-based skills training intervention that aims to improve knowledge about one's level and sources of motivation, the ability to monitor and regulate (understand and manage) motivation, so that one can better initiate and sustain goal-directed behavior. Participants who consent for research will complete assessments of motivation, goal attainment, quality of life, executive functioning, community functioning, and psychiatric symptoms severity. The intervention phase will be approximately 12 weeks in duration and will entail weekly MST group sessions. At treatment endpoint, participants will be asked to repeat the assessment battery from baseline as well as a satisfaction survey. Change in motivation, goal attainment and quality of life will indicate whether MST is engaging the hypothesized target (motivation) and whether there is impact on functioning.

Conditions

Schizophrenia; Schizoaffective Disorder

Keywords

Motivation; Skills Training

Outcome Measures

Primary Outcomes (2)

• Change in Motivation and Pleasure Scale (MAP)

  MAP is an interviewer rated measure of motivation, pleasure, and engagement in work, school, recreational and social activities. Possible total scores range from 0 to 36, with lower scores indicating better outcomes. The average MAP score ranges from 0-4 with lower scores indicating better outcomes.

  Baseline and up to 14 weeks

• Change in Goal Attainment Scaling (GAS)

  GAS measures progress towards personal goal attainment, rated along a continuum of predetermined successful outcomes on a scale from 0 to 10. Higher scores indicate better outcomes.

  Baseline and up to 14 weeks

Secondary Outcomes (1)

• Change in Heinrichs Carpenter Quality of Life Scale (QLS)

  Baseline and up to 14 weeks

Study Arms (1)

Motivation Skills Training (MST)

EXPERIMENTAL

Participants will complete a baseline assessment, receive weekly MST sessions in a group format for a duration of 12 weeks, and will then repeat the assessment battery from baseline as well as a satisfaction survey.

Behavioral: Motivation Skills Training (MST)

Interventions

Motivation Skills Training (MST) BEHAVIORAL

MST is a weekly group-based skills training intervention that aims to improve knowledge about one's level and sources of motivation, the ability to monitor and regulate (understand and manage) motivation, so that one can better initiate and sustain goal-directed behavior.

Motivation Skills Training (MST)

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age 18-65
• A primary Diagnostic and Statistical Manual of Mental Disorders (DSM)-5 diagnosis of schizophrenia or schizoaffective disorder
• Medically and psychiatrically stable outpatient status
• English Fluency

You may not qualify if:

• Indications of Intellectual Disability as documented in medical history or measured by \< 70 premorbid full scale Intelligence Quotient (IQ) estimate
• Severe substance use within the past 3 months determined by DSM-5 criteria
• Neurologic condition causing brain disease
• Mild to severe cognitive impairment associated with possible dementia

Sponsors & Collaborators

• Columbia University: lead
• National Institute of Mental Health (NIMH): collaborator

Study Sites (1)

The Bridge Inc

New York, New York, 10025, United States

Location

MeSH Terms

Conditions

Schizophrenia; Psychotic Disorders

Condition Hierarchy (Ancestors)

Schizophrenia Spectrum and Other Psychotic Disorders; Mental Disorders

Results Point of Contact

• Title: Dr. Alice Saperstein
• Organization: Columbia University

ams2334@cumc.columbia.edu

646-774-8464

Study Officials

• Alice Saperstein, PhD

  Columbia University

  PRINCIPAL INVESTIGATOR

Publication Agreements

• PI is Sponsor Employee: No
• Restrictive Agreement: No

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor of Medical Psychology (in Psychiatry)

Model Details: Open Trial

Study Record Dates

• First Submitted: February 17, 2023
• First Posted: February 27, 2023
• Study Start: May 30, 2023
• Primary Completion: October 31, 2023
• Study Completion: December 31, 2023
• Last Updated: December 18, 2024
• Results First Posted: December 18, 2024

Record last verified: 2024-11

Data Sharing

• IPD Sharing: Will share
• Time Frame: A list of all data expected will be submitted by July 10, 2023. Subsequently raw data will be submitted on a semi-annual basis. Unpublished de-identified data will be submitted prior to study completion and will be shared within one year after project completion or when the data are published, whichever is earlier.
• Access Criteria: Data in NIH repositories may be accessed through the NIH Data Access Committee which reviews data access and submission requests.

Locations

US (1)