Trials Sponsors Conditions Drugs Pricing

Conditions

Leukoplakia, Oral Oral Lichen Planus Potentially Malignant Lesions

Keywords

lncRNA DQ786243salivaoral potentially malignant lesionsmiRNA146a

Outcome Measures

Primary Outcomes (1)

salivary expression of lncDQ786243 in OLP, Leukoplakia, control
2 months

Secondary Outcomes (1)

salivary expression of miRNA146a in OLP, Leukoplakia, control
2 months

Study Arms (3)

Oral Lichen Planus

Diagnostic Test: Real-time Polymerase Chain Reaction technique

Leukoplakia

Diagnostic Test: Real-time Polymerase Chain Reaction technique

Healthy control

Diagnostic Test: Real-time Polymerase Chain Reaction technique

Interventions

Real-time Polymerase Chain Reaction techniqueDiagnostic test

Real-time Polymerase Chain Reaction technique

Healthy controlLeukoplakiaOral Lichen Planus

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

Eligibility Criteria

Sexall

Healthy VolunteersYes

Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

Sampling MethodNon-Probability Sample

Study Population

Egyptian Population

You may qualify if:

participants will be divided into 3 groups:

Sponsors & Collaborators

Fayoum University
Otherlead

Study Sites (1)

Fayoum University

Al Fayyum, Egypt

Related Publications (1)

Afifi S, Ibrahim S, Kotb AA, ElRefai S, Hafed L, Shaker O, Baz S, Shalaby R. Long noncoding RNA DQ786243 and miRNA146a as potential salivary biomarkers for selected oral potentially malignant disorders: a diagnostic accuracy study. Oral Surg Oral Med Oral Pathol Oral Radiol. 2026 Jan;141(1):96-105. doi: 10.1016/j.oooo.2025.08.013. Epub 2025 Aug 27.
PMID: 40973523DERIVED

MeSH Terms

Conditions

Lichen Planus, OralLeukoplakia, Oral

Condition Hierarchy (Ancestors)

Mouth DiseasesStomatognathic DiseasesLichen PlanusLichenoid EruptionsSkin Diseases, PapulosquamousSkin DiseasesSkin and Connective Tissue DiseasesMouth NeoplasmsHead and Neck NeoplasmsNeoplasms by SiteNeoplasmsLeukoplakiaPrecancerous Conditions

Enrollment

45 participants (actual enrollment reported by the registry).

Study Design

Study Type: observational
Observational Model: OTHER
Time Perspective: PROSPECTIVE
Sponsor Type: OTHER
Responsible Party: PRINCIPAL INVESTIGATOR
PI Title: Lecturer

Study Record Dates

First Submitted

February 7, 2023

First Posted

February 16, 2023

Study Start

November 1, 2022

Actual (reported)

Diagnostic Accuracy of lncRNA DQ786243 and miRNA146a in Saliva of Oral Potentially Malignant Lesions

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (1)

Study Arms (3)

Oral Lichen Planus

Leukoplakia

Healthy control

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

Related Publications (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (1)

Study Arms (3)

Oral Lichen Planus

Leukoplakia

Healthy control

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

Related Publications (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations